B) Dominant microbes model: An alternative hypothesis would be that given the dominance of a small number of microbe species composing the vast majority of microbes in the gut, the concentration of each metabolite is determined by the most frequent microbe. This conceptualization translates into mode...
Mucosal and barrier tissues, such as the gut, lung or skin, are composed of a complex network of cells and microbes forming a tight niche that prevents pathogen colonization and supports host–microbiome symbiosis. Characterizing these networks at high molecular and cellular resolution is crucial for...
Posts about Human gut written by Svetlana Ugarcina Perovic, Axel Künstner, Feargal, JP Cardenas, and Grace Deitzler
1). The FMT experiments suggest that the gut microbiota is required for the protective effect of Mel on neuroinflammation, apoptosis, and memory impairment induced by SD. FMT treatment modulates gut microbiota composition in recipient mice To test whether FMT modulated gut microbiota, we performed ...
[7] Ruhlemann MC, Degenhardt F, Thingholm LB, Wang J, Skieceviciene J, Rausch P, et al. Application of the distance-based F test in an mGWAS investigating beta diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci. Gut Microbes. 2018;9(1):68-75...
The gut microbiome (GM) can influence many biological processes in the host, impacting its health and survival, but the GM can also be influenced by the host’s traits. In vertebrates, Major Histocompatibility Complex (MHC) genes play a pivotal role in c
Two-sided Wilcoxon test. ***P < 0.001; **P < 0.01; *P < 0.05. d, Abundance-based significance or NetMoss score for each genus. Red dots represent microbial markers in the gutMDisorder database, and gray dots represent other bacteria. The two dashed blue lines indicate Net...
The incidence of young-onset colorectal cancer (yCRC) has been increasing in recent decades, but little is known about the gut microbiome of these patients. Most studies have focused on old-onset CRC (oCRC), and it remains unclear whether CRC signatures
Recent evidence supports the importance of the gut microbiota (GM) in the modulation of multiple functions associated with depression through the gut-brain axis (GBA). However, the underlying mechanisms remain poorly understood. Therefore, in the current study, we aimed to screen the microbiota out...
The gut microbiome is closely associated with health status, and any microbiota dysbiosis could considerably impact the host’s health. In addition, many active consortium projects have generated many reference datasets available for large-scale retrospe