Advances in DNA sequencing technology combined with new biocomputational tools enable scientists to describe our microbial environment with unprecedented precision.Owyang,C.Wu,G.D.GastroenterologyOwyang C, Wu GD (2014) The gut microbiome in health and disease. Gastroenterology 146:1433–1436. : 10....
B. The gut microbiome in health and in disease. Curr. Opin. Gastroenterol. 31, 69 (2015). Article PubMed PubMed Central CAS Google Scholar Cho, I. & Blaser, M. J. The human microbiome: at the interface of health and disease. Nat. Rev. Genet. 13, 260–270 (2012). Article Pub...
The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut ...
“other genome” could play an important role in immune-related, complex diseases, and growing evidence supports a causal role for gut microbiota in regulating predisposition to diseases. A comprehensive analysis of the human gut microbiome is thus important to unravel the exact mechanisms by which ...
Any perturbation in host-microbiota crosstalk can be an initiating or reinforcing factor in disease pathogenesis. A large array of metabolites drives the crosstalk between the host and its microbiome. The three currently most studied categories of metabolites involved in host-microbiota interactions are ...
Many practicing clinicians may be unaware of the essential role that the microbiome plays in both health and disease. This review aims to improve clinical understanding of the gut microbiome by discussing key terminology and foundational concepts. The role of a healthy microbiome in normal host ...
Gut microbiome in health and disease: linking the microbiome-gut-brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative ... S Ghaisas,J Maher,A Kanthasamy - 《Pharmacology & Therapeutics》 被引量: 95发表: 2016年 The gut-brain axis, including the microbiome, ...
As research in this area continues to evolve, it is likely that we will gain a deeper understanding of the role of the gut microbiome in health and disease, and new interventions will emerge to help promote a healthy gut microbiome and prevent the development of chronic diseases....
(RECENT ADVANCES IN BASIC SCIENCE)肠道微生物群与健康:机制性见解 Gut microbiome and health: mechanistic insights Willem M de Vos, Herbert Tilg, Matthias Van Hul, et al. doi: 10.1136/gutjnl-2021-326789 另外,BMJ还就炎性肠病(INFLAMMATORY BOWEL DISEASE)主题整理了旗下期刊发表的最有影响力的十篇文...
2024年6月6日,上海交通大学医学院附属瑞金医院研究团队在Nature Medicine(自然·医学)上发表题为Divergent age-associated and metabolism-associated gut microbiome signatures modulate cardiovascular disease risk(不同年龄相关和代谢相关肠道微生物特征调节心血管疾病风险),该研究在一个由10207名40-93岁个体组成的发现队...