Microbiomedysbiosischronic diseasesautoimmune diseasestype 1 diabetesceliac diseaseinflammatory bowel diseaseThe early gastrointestinal microbiome plays a critical role in the future health status of infants and young children, and early dysbiosis has been associated with the development of several chronic ...
The gut microbiome, i.e., the community of bacteria and other microorganisms living in the human gut, has been implicated both directly and indirectly (mediating the effects of diet) on human health [1,2]. The associations between gut microbiome composition and disease status have been widely ...
introduced the Human Intestinal Metagenome Initiative (HIMI), while the 'Human Microbiome Project (HMP)' initiated by the National Institutes of Health (NIH), was subsequently launched to undertake an extensive investigation into the crucial role of the gut microbiome in human health and disease [3...
As such, cardiometabolic comorbidities are common in PLWH and associated with inflammation. Identifying modifiable risk factors is therefore of utmost biomedical importance. The microbiome could be one of several driving factors, along with viral replication, ART toxicity, lipodystrophy, traditional risk fa...
Despite modern antiretroviral therapy (ART), people living with HIV (PLWH) have increased relative risk of inflammatory-driven comorbidities, including cardiovascular disease (CVD). The gut microbiome could be one of several driving factors, along with t
(age, region, body mass index, physical exercise, smoking habits, and alcoholic drink, and yogurt consumption) were found to have different effects on the gut microbiome of healthy Chinese people. We also examined the distribution patterns of disease-related microorganisms (DRMs), revealing which ...
The role of lung and gut microbiota in the pathology of respiratory diseases. 3.1. Direct Interaction between Lung and Gut Microbiome The microorganisms that have colonized the mucosa of the respiratory and digestive tracts can have a regulatory effect on tissues and are the material basis for lung...
Given the established role of the gut microbiota in the development and progression of CKD and its complications, favorable modification of the composition and function of the gut microbiome represents an appealing therapeutic target for prevention and treatment of CKD. This review provides an overview...
Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death globally, and manifests as a progressive inflammatory lung disease with no curative treatment. The lung microbiome contributes to COPD progression, but the function of the gut microbiome remains unclear. Here we examin...
et al. Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease. Gut 65, 830–839 (2016). CAS PubMed Google Scholar Ma, C. et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science. 360, eaan5931 (2018). Bonneville, ...