Microbiomedysbiosischronic diseasesautoimmune diseasestype 1 diabetesceliac diseaseinflammatory bowel diseaseThe early gastrointestinal microbiome plays a critical role in the future health status of infants and young children, and early dysbiosis has been associated with the development of several chronic ...
The gut microbiome, i.e., the community of bacteria and other microorganisms living in the human gut, has been implicated both directly and indirectly (mediating the effects of diet) on human health [1,2]. The associations between gut microbiome composition and disease status have been widely ...
introduced the Human Intestinal Metagenome Initiative (HIMI), while the 'Human Microbiome Project (HMP)' initiated by the National Institutes of Health (NIH), was subsequently launched to undertake an extensive investigation into the crucial role of the gut microbiome in human health and disease [3...
Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death globally, and manifests as a progressive inflammatory lung disease with no curative treatment. The lung microbiome contributes to COPD progression, but the function of the gut microbiome remains unclear. Here we examin...
Given the established role of the gut microbiota in the development and progression of CKD and its complications, favorable modification of the composition and function of the gut microbiome represents an appealing therapeutic target for prevention and treatment of CKD. This review provides an overview...
Integrated analyses of microbiome with metabolome revealed a remarkable shift of gut microbiota and metabolites in HBV-CLD patients, and disease progression and antiviral treatment were found to be two main contributing factors for the shift. Concordant decreases in Turicibacter with 4-hydroxyretinoic ...
pathologies. The gut microbiome (GMB) is comprised of trillions of bacteria, archaea, protozoa, viruses, and fungi and has been shown to potentially regulate neuroinflammation in a variety of neurological conditions, including Multiple Sclerosis [2], Parkinson’s disease [3,4], and AD [5,6,7...
Interest in the interplay between host genetics and the gut microbiome in complex human diseases is increasing, with prior evidence mainly being derived from animal models. In addition, the shared and distinct microbiome features among complex human dise
(age, region, body mass index, physical exercise, smoking habits, and alcoholic drink, and yogurt consumption) were found to have different effects on the gut microbiome of healthy Chinese people. We also examined the distribution patterns of disease-related microorganisms (DRMs), revealing which ...
Intersections between microbiome and heart failure: revisiting the gut hypothesis. J Card Fail. 2015;21:973–80. CAS PubMed PubMed Central Google Scholar Kanbay M, Onal EM, Afsar B, Dagel T, Yerlikaya A, Covic A, et al. The crosstalk of gut microbiota and chronic kidney disease: ...