In addition, we found that the expression of phospho-GSK-3b was related with the accumulation of b-catenin in surrounding tissues (p < 0.05). The expression of phospho-GSK-3b and its association with the development of HCC is reported for the first time. In addition, this is the first ...
β-catenin介导的Wnt信号通路涉及各种组织和器官的发育,包括颅面结构[5]。在小鼠胚胎发育过程中,Gsk-3β对于上颚形成至关重要,Gsk-3β在调节胚胎干细胞系中的Wnt/βcatenin信号传导中发挥冗余功能[6]。Gsk-3β突变杂合子的小鼠看起来正常且有生育能力,但通过Gsk3b+/-小鼠之间的杂交获得的Gsk3b-/-小鼠表现出完...
mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling...
mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling...
(PI3K)/Akt. Moreover, in terms of EMT markers, CD44 downregulated E-cadherin expression, upregulated N-cadherin, α-actin,vimentin,fibronectinand MT1-MMP expression and inhibited the formation of the membrane-associated E-cadherin–β-catenin complex, which resulted in cell invasion and migration....
N-glycosylation of CD82 at Asn157 is required for suppressing migration and invasion by reversing EMT via Wnt/β-catenin pathway in colon cancer Authors - Lin Zhu View Article human WB Front Pharmacol Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway Authors...
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response. Authors - Wenjun Wang View Article zebrafish WB Nat Commun ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling. Authors - Xiaoyun Sun View Article See more citationsProteintech...
Cat No.15113-1-AP Freight/Packing:-- Country/Region Please contact our China branch Proteintech Guarantee Request bulk or custom quote humanWB The Role of miR-640: A Potential Suppressor in Breast Cancer via Wnt7b/β-catenin Signaling Pathway. ...
Intermedin protects HUVECs from ischemia reperfusion injury via Wnt/β-catenin signaling pathway. Author: Yanhong Wang, et. al. Year: 2019 Journal: Cancer Manag Res Applications: Unspecified Reactivity: Unspecified Title: Upregulation of family with sequence similarity 83 member D expression enhances...
Print datasheet MSDS -/- Cat No.22104-1-AP Freight/Packing:- Country/Region Size/Concentration Quantity Proteintech Guarantee Request bulk or custom quote humanWB Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition ...