中文名称: 化合物 GSK3-IN-3 英文名称: GSK3-IN-3 CAS号: 331963-27-0 品牌: TargetMol 产地: 美国 保存条件: Shipping with blue ice. 纯度规格: 99.37% 产品类别: 抑制剂 货号: T73331 Product Introduction Bioactivity 名称 GSK3-IN-3 描述 GSK3-IN-3 is a mitochondrial autophagy (...
GSK3-IN-3 (VP07)(25 μM;24 小时)在表达 Parkin 的 U2OS-iMLS 细胞中诱导线粒体自噬,但效力有限。 GSK3-IN-3(1.56-25 μM;24 小时)导致 U2OS-iMLS-Parkin 细胞发生线粒体分裂和线粒体形态变化。 GSK3-IN-3 (VP0.7)(5 μM,10 μM;)在 SH-SY5Y 细胞的帕金森病体外细胞模型中显示出针对 6-...
GSK3-IN-1是一种 GSK3B-糖原合酶激酶3β抑制剂。 规格价格库存数量 1 mg¥ 257现货 5 mg¥ 598现货 10 mg¥ 1,090现货 25 mg¥ 2,390现货 50 mg¥ 3,400现货 100 mg¥ 4,750现货 200 mg¥ 6,390现货 1 mL x 10 mM (in DMSO)¥ 708现货 ...
Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that functions in numerous signaling pathways initiated by diverse stimuli. The functions of GSK-3 in cancer differ depending on cell type. In the present study, we examined the effects of a specific GSK-3 inhibitor on the regul...
The Wnt-signaling pathway, which includes GSK-3, is important in bone metabolism. The small molecule drug AZ2858 inhibits GSK-3. Oral administration of AZD2858 increases bone mineral density and content in rats. This increase enhances both vertebral compression and diaphyseal bending strength. AZD...
英文名称: GSK3-IN-1 总访问: 30 国产/进口: 进口 半年访问: 14 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg 最后更新: 2024-11-4 货号: HY-Q48328 CAS 号: 478482-74-5 参考报价: 1430; 520; 1300; 2200; 4800; 7380 立即询价 电话...
GSK-3 also regulates other critical signaling pathways which may contribute to the therapeutic effects of lithium, including growth factor/neurotrophin signaling downstream of Akt. Here we will review the roles of GSK-3 in CNS development and adult neurogenesis, with a focus on the canonical Wnt ...
GSK-3β overexpression led to a general reduction in the number of dendritic spines. In addition, it caused a slight reduction in the percentage, head diameter and length of thin spines, whereas the head diameter of mushroom spines was increased. 展开 ...
Arabidopsis glycogen synthase kinase 3 (GSK3)-like kinases have versatile functions in plant development and in responding to abiotic stresses. Although physiological evidence suggested a potential role of GSK3-like kinases in abscisic acid (ABA) signaling, the underlying molecular mechanism was largely...
The GSK-3beta/PARP-1 relationship was investigated. Adult (4 months) and old (24 months) rats were used. PARP-1 inhibitor 3-aminobenzamide (3-AB) was injected subcutaneously for 5 days in a dose of 10 and 30 mg/kg b.w. On the 8th day object recognition test and open field test ...