.; [Gasdermin-D, C-terminal]: Cytoplasm, cytosol . 组织表达: Expressed in the suprabasal cells of esophagus, as well as in the isthmus/neck, pit, and gland of the stomach, suggesting preferential expression in differentiating cells. GSDMD N-terminal rabbit pAb Catalog No PLA021446 Product...
Fig : Western blot analysis of GSDMD N-terminal on different lysates. Proteins were transferred to a NC membrane and blocked with 5% NF-Milk in TBST for 1 hour at room temperature. The primary antibody (AWA10007, 1/1000) was used in PBST at room temperature for 2 hours. Goat Anti-Rabbi...
Plasma membrane perforation elicited by caspase cleavage of thegasderminD (GSDMD) N-terminal domain (GSDMD-NT) triggerspyroptosis. The mechanisms underlying GSDMD membrane translocation and pore formation are not fully understood. Here, using a proteomics approach, we identified fatty acid synthase (FAS...
2022年11月2日，南京医科大学杨硕课题组和南京中医药大学胡刚/王冰微课题组合作，在PNAS杂志发表题为“The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11”的研究论文，揭示了固有免疫细胞焦亡效应分子GSDMD负反馈调控炎症小体激活的...
primarily prevent pyroptosis by modifying human/mouse C191/C192 in the N-terminal fragment of GSDMD. However, cysteine modification can prevent the function of important proteins or enzymes, thereby leading to adverse reactions. Here, we chose an alternative key intervention site for GSDMD activation...
点击查看官网产品详细介绍:人GSDMD-N重组蛋白/Recombinant Human GSDMD-N来源于:E.Coli,表达区间:1-275,适用种属:Human 产品介绍 产品名称 Recombinant Human GSDMD-N 产品货号 P9442 Uniprot ID P57764 种属 Human 来源 E.Coli 表达区间 1-275 预测分子量 51.1 kDa 标签 N-terminal His-IF2DI Tag 纯度 Great...
RatGSDMDProteinN-terminalFragment(GSDMD-N)ELISAResearchKit 快递: 顺丰 指标缩写: GSDMD-N 检测指标: 透明带精子结合蛋白3 价格说明 价格:商品在平台的展示标价,具体的成交价格可能因商品参加活动等情况发生变化,也可能随着购买数量不同或所选规格不同而发生变化,如用户与商家线下达成协议,以线下协议的结算价格...
2022年11月2日,南京医科大学杨硕课题组和南京中医药大学胡刚/王冰微课题组合作,在PNAS杂志发表题为“The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11”的研究论文,揭示了固有免疫细胞焦亡效应分子GSDMD负反馈调控炎症小体激活的作...
2022年11月2日,南京医科大学杨硕课题组和南京中医药大学胡刚/王冰微课题组合作,在PNAS杂志发表题为“The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11”的研究论文,揭示了固有免疫细胞焦亡效应分子GSDMD负反馈调控炎症小体激活的作...
2022年11月 2日,南京医科大学杨硕课题组和南京中医药大学胡刚/王冰微课题组合作,在PNAS杂志发表题为The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/1...