应用类型 WB, IF/ICC 免疫原 Recombinant fusion protein of human GSDMD(NP_079012.3). 来源宿主 Rabbit 反应性 Human, Mouse, Rat 保存建议 Store at 4 其他 Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品...
GSDMD is currently being widely explored as a drug target. Existing inhibitors targeting GSDMD, such as necrosulfonamide, disulfiram, and fumarate, primarily prevent pyroptosis by modifying human/mouse C191/C192 in the N-terminal fragment of GSDMD. However, cysteine modification...
Phe232~His484 (Accession # P42336), with N-terminal His Tag 来源宿主 Rabbit 反应性 Human 保存建议 Store at 2 其他 Biomatik公司于2002年在加拿大成立,是生物试剂一站式购物中心,提供29000+ELISA试剂盒,27000+抗体,17000+重组蛋白,280+生物试剂。除了目录产品外,Biomatik还为全球的研究人员提供62,000多种定...
Plasma membrane perforation elicited by caspase cleavage of the gasdermin D (GSDMD) N-terminal domain (GSDMD-NT) triggers pyroptosis. The mechanisms underlying GSDMD membrane translocation and pore formation are not fully understood. Here, using a proteomics approach, we identified fatty acid synthase ...
Synonyms: DF 5L; DF5L; DFNA 5L; DFNA5L; FKSG 10; FKSG10; FLJ12150; Gasdermin D; Gasdermin domain containing 1; Gasdermin domain containing protein 1; Gasdermin domain-containing protein 1; Gasdermin-D; GasderminD; GSDMD_HUMAN; GSDMDC 1; GSDMDC1; Gasdermin-D, N-terminal; GSDMD-NT; h...
抗体名: DF 5L; DF5L; DFNA 5L; DFNA5L; FKSG 10; FKSG10; FLJ12150; Gasdermin D; Gasdermin domain containing 1; Gasdermin domain containing protein 1; Gasdermin domain-containing protein 1; Gasdermin-D; GasderminD; GSDMD_HUMAN; GSDMDC 1; GSDMDC1; Gasdermin-D, N-terminal; GSDMD-NT; h...
N-terminal degradation activates the Nlrp1b inflammasome[J]. Science, 364(6435): 82-5. [18]Zhang WS, Chronis C, Chen X, et al. The BAF and PRC2 complex subunits Dpf2 and eed antagonistically converge on Tbx3 to control ESC differentiation[J]. Cell Stem Cell, 2019, 24(1): 138-52...
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(22915-1-AP)和caspase-1抗体(12544-1-AP)购自武汉三鹰生物技术有限公司;消皮素D N端片段(gasdermin D N-terminal fragment, GSDMD-N)抗体(DF12275)购自Affinity;NLRP3抗体(bs-23723R)购自博奥森生物技术有限公司;TriQuick Reagent...
(IECs) constitute the primary barrier between host cells and numerous foreign antigens; it is unclear how IECs induce the protective immunity against pathogens while maintaining theimmune toleranceto food. Here, we found IECs accumulate a less recognized 13-kD N-terminal fragment ofGSDMDthat is ...