The research suggests that Gs, Gi, and Gq receptors play crucial roles in regulating glucagon secretion and glucose homeostasis, offering new avenues for combating metabolic diseases.Kitamura, TadahiroJournal of Diabetes Investigation
We have shown that activation of SKM Gq-coupled receptors has a beneficial effect on whole-body glucose homeostasis by promoting glucose uptake into SKM [10]. In this study, we explored the in vivo metabolic effects caused by acute activation of SKM Gs-coupled receptors. Analysis of mutant ...
In contrast, the stimulatory effect observed with CNO-treated hM3Dq-AgRP mice lasted only for a single day (Fig. 3d–f), most likely reflecting differences in cellular activity caused by the activation of Gs- versus Gq-dependent signalling pathways (Figs 1c and 2). AgRP neurons store and ...
Long-term effects of lysine concentration on growth performance, intestinal microbiome, and metabolic profiles in a pig model.,Food &Function,2018,通讯作者(9)Reiter RJ, Zhang D, Zhu C, Zhu GQ, Ren WK*, Yin YL. Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high-...