As such, histologic grade was incorporated into the latest 8th edition of the American Joint Committee on Cancer breast cancer staging system. In this study, we hypothesized that grade 3 breast cancers demonstrate aggressive molecular biological profiles, reflecting worse biology and possible underlying ...
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We report on a 45-year-old woman with breast cancer, positive for human epidermal growth factor receptor 2 by immunohistochemistry score 3+, who was treated in an adjuvant setting with trastuzumab and developed severe neutropenia. Twenty seven weeks after initiation of trastuzumab, the patient ...
The DEGs obtained in each comparison are provided in supplementary datasheet 1, 2 and 3. The obtained DEGs in grade 1 across all eight datasets were analyzed with UpSetR package in R to find the common DEGs. The same procedure was repeated for DEGs of grade 2 and grade 3 breast cancer ...
Correction to: Palbociclib use with grade 3 neutropenia in hormone receptor-positive metastatic breast cancerIn the original publication of the article, under the Results section, subheading "Patient survival", the second sentence that reads as "The 6-month PFS was 92.4%, 81.8%, and 93.3% and ...
摘要: To assess the knowledge and attitude of self-medication practice, commonly used medicines, factors responsible for self-medication and end result of this practice会议名称: 12th Asian-Pacific Congress of Clinical Biochemistry (APCCB 2010) ...
breast cancerECMmass spectrometryTN tumorsTumor extracellular matrix (ECM) plays a pivotal role in outcome of breast cancer (BC) patients. Overespression of 58 genes, encoding 43 structural ECM proteins, has been identified to determine a specific cluster of BC with accelerated metastatic potential ...
9Department of Pathology, Nagoya National Hospital, Nagoya, Japan and 10Department of Pathology, University of Nottingham, Nottingham, UK Adenoid cystic carcinoma of the breast is a rare histological type of triple-negative breast cancer with an indolent clinical behavior, often driven by the MYB-NF...
Here, we present an analysis of the validity of histological grade as a prognostic factor and a consensus view on the significance of histological grade and its role in breast cancer classification and staging systems in this era of emerging clinical use of molecular classifiers....
Here, we investigated the safety of a new dose scheme for palbociclib, which avoids dose delays or reductions due to afebrile grade 3 neutropenia.MethodsA consecutive cohort of ER( +)/HER2( ) advanced breast cancer patients who received palbociclib between 2017 and 2018 was analyzed. The ...