WHO grade III meningioma: De novo tumors show improved progression free survival as compared to secondary progressive tumorsdoi:10.1016/j.jocn.2021.05.060Jacob RuzevickAlec W GibsonPhilip D TatmanManuel Ferreira
WHO grade II meningioma: a retrospective study for outcome and prognostic factor assessment Article 16 June 2016 World Health Organization grade II meningiomas Article 28 March 2016 Extent of resection and survival outcomes in World Health Organization grade II meningiomas Article 17 November 2020...
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Crude and adjusted Cox proportional hazards regression models were used to evaluate for differences in survival. Results: A total of 287 patients with WHO grade II or grade III spinal meningioma (white, n = 237; black, n = 32; Asian and Pacific Islander, n = 11; unknown race, n = 7)...
This study aimed to evaluate factors affecting survival. METHODS. We performed a multi-institutional retrospective chart review study of patients with HGM (defined as grade 2 or 3 meningioma) whose tumor had undergone next-generation sequencing. Statistical testing was performed in Stata/MP version ...
Purpose High-grade gliomas (HGG) represent a challenging subset of brain tumors characterized by aggressive nature and poor prognosis. Histopathology remains to be the standard for diagnosis, however, it is invasive, prone to sampling errors, and may not capture the full tumor heterogeneity and evol...
Lovastatin is a potent inhibitor of meningioma cell proliferation: evidence for inhibition of a mitogen associated protein kinase. Lovastatin inhibits 3-hydroxy 3-methylglutaryl coenzyme A (HMG-CoA) reductase the rate limiting enzyme for synthesis of mevalonic acid, a precursor for cho... MD Johnson...
There is a need to better understand meningioma oncogenesis for biomarker discovery and development of targeted therapies. Histological or genetic criteria do not accurately predict aggressiveness. Post-translational studies in meningioma progression are lacking. In the present work, we introduce a combinat...
The role of adjuvant radiotherapy after gross total resection (GTR) of WHO grade 2 meningioma remains unclear, and conflicting results have been published.
We previously reported that expression of dickkopf-3 (DKK3), which is involved in the Wnt/β-catenin pathway, is significantly associated with prognosis in patients with glioblastoma multiforme (GBM). The aim of this study was to compare the association