Gr-1 + myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism. Journal of immunology. 171, 726-732, doi:10.4049/jimmunol.171.2.726 (2003).Dupuis M, De Jesús Ibarra-Sánchez M, Tremblay ML, Duplay ...
in vivo depletion of Gr-1+ myeloid cells, Flow Cytometry Bodogai, M., et al. (2015). "Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells" Cancer Res 75(17): 3456-3465. ...
Interferon regulatory factor-8 modulates the development of tumor-induced CD11b+Gr-1+ myeloid cells. J Cell Mol Med. 2009;13(9B):3939-3950.Stewart TJ,Greeneltch KM,Reid JE, et al.Interferon Regulatory Factor-8 Modulates the Development of Tumor-Induced CD11b+Gr-1+ Myeloid Cells. Journal ...
Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells...
The myeloid differentiation antigen Gr-1 is a member of the Ly-6 family, Ly-6G (1). The RB6‑8C5 antibody also reacts weakly with Ly-6C-transfected EL4 cells (2). In the periphery, this antibody specifically recognized granulocytes (3, 4). ...
CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress. J Immunol. 2006;176:2085Y2094.Makarenkova, V. P., V. Bansal, B. M. Matta, L. A. Perez, and J. B. Ochoa. 2006. CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic ...
Related Research Areas Inflammatory/Monocyte-derived Dendritic Cells Monocyte Markers Mouse Tissue-Resident Macrophage Markers Myeloid Lineage Markers Myeloid-derived Suppressor Cells (MDSC) Plasmacytoid Dendritic Cells Serine Proteases and Regulators
应用:in vivo depletion of Gr-1+ myeloid cells Flow cytometry Immunohistochemistry (paraffin) Immunohistochemistry (frozen) 产品形式:PBS, pH 7.0 Contains no stabilizers or preservatives 内毒素:<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay ...
(GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a ...
in vivodepletion of Gr-1+ myeloid cells Flow cytometry Immunohistochemistry (paraffin) Immunohistochemistry (frozen) Endotoxin <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay Purity >95% Determined by SDS-PAGE Formulation PBS, pH 7.0 ...