Expression of two myeloid cell-specific genes requires the novel transcription factor, c- fes expression factor. J Biol Chem. 1997; 272 :29527–29537.Heydemann A, Boehmler JH, Simon MC. Expression of two myeloid cell-specific genes requires the novel transcription factor, c-fes expression ...
monocytogenesare prone to systemic infections and acute death, whereas germ-free mice recolonized with a complex microbiota can develop resistance toListeriamonocytogenes.Germ-free mice also exhibited diminished proportions and differentiation of specificmyeloid cell progenitorsin theyolk sacand bone marrow....
The overlap between each pair of cell type-specific and tissue region-specific gene sets was analyzed using MIA (c4). The significance of the intersection was displayed using the hypergeometric distribution. (c5). The numbers of cell subtype-specific and tissue region-specific genes used in the ...
Myeloid cell-specific Sirt6 deficiency decreases M2 macrophage infiltration into skin wounds We examined the infiltration of macrophages, which are critical inflammatory cells for wound healing, into wound sites by counting F4/80-positive cells. The accumulation of F4/80-immunopositive cells was signifi...
Myeloid cell leukemia-1 (Mc1-1) is a candidate target gene of hypoxia-inducible factor-1 (HIF-1) in the testis. Abstract Spermatic cord torsion can lead to testis ischemia (I) and subsequent ischemia-reperfusion (I/R) causing germ cell-specific apoptosis. Previously, we demonstrated tha...
Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration Article Open access 05 September 2018 References Kluge MG, Kracht L, Abdolhoseini M, Ong LK, Johnson SJ, Nilsson M. Impaired microglia process dynamics post-stroke are specific to sites of secondary neur...
et al. Myeloid-specific targeting of Notch ameliorates murine renal fibrosis via reduced infiltration and activation of bone marrow-derived macrophage. Protein Cell 10, 196–210 (2019). https://doi.org/10.1007/s13238-018-0527-6 Download citation Received28 November 2017 Accepted28 February 2018 ...
Myeloid cellsare important effector cells in the injured spinal cord tissue.Microgliaand monocyte-derived macrophages serve important functions in the injured spinal cord, and their distinctive roles can now be studied more efficiently with the help of reporter mice and cell specific markers that were...
DCs appear to be generated mainly frommyeloid progenitor cellsand are found in alllymphoid tissuewhere they have specific names as skin langerhans DC,follicular DCingerminal centers, andinterdigitating cellsin T-cell zone ofLNsor the spleen. They have highly efficient function inantigen presentation,...
Efficient sequence specific gene silencing of myeloid cell leukemia sequence 1 is possible through the use of siRNA technology. By selecting particular siRNAs directed to myeloid cell leukemia sequence 1 by rationale design, one can maximize the generation of an effective gene silencing reagent, as we...