Download: Download full-size image Fig. 2. Gq/G11 mutations promote PD-L1 expression. (A) The correlation of expression between PD-L1 and YAP in UM patients was analyzed using TCGA data. (B, C) The correlation of expression between PD-L1 and GNAQ (B)/GNA11 (C) in UM patients was...
Check access to the full text by signing in through your organization. Access through your organization Section snippets Plasmids To make His6-RGS3 and His6-RGS3CT (amino acids 314–520) polymerase chain reaction (PCR) fragments generated from RcCMV-RGS3 were inserted into the NdeI/XhoI ...
observed in class A GPCRs20. The mutant hmGlu5-ΔCter-A856 had a pEC50of 4.35 ± 0.06 (n = 5) for glutamate and 7.34 ± 0.18 (n = 5) for quisqualate (Fig.1Aand Supplementary2). These values were similar to those obtained for the full-length wild-type (WT...
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