GPCR_Pathway之经典信号通路.ppt,SRF Elk-1 C-Jun C-Fos STATs NF-KB NFAT GP C R GTP GTP GTP GTP GTP GDP PYK2 Paxillin P P P BCL10 BIMP1 SRF Elk-1 c-Jun c-Fos STATs NFAT Gene Expression GPCR Pathway GP C R GP C R GP C R GP C R GP C R Ga 12/13 LARG Rho ROCK S
Genome-wide screening for the G-protein-coupled receptor (GPCR) pathway-related therapeutic gene RGS19 (regulator of G protein signaling 19) in bladder cancerBladder cancer is one of the most severe genitourinary cancers, causing high morbidity worldwide. However, the underlying molecular mechanism ...
GPCR信号通路发现者PCR芯片(GPCR Signaling PathwayFinder PCR Array)(促) 启因生物对GPCRs,以及介导的cAMP/PKA信号通路、PKC/MEK信号通路的相关基因实行促销活动。 G蛋白偶联受体(GPCR)是一个庞大的细胞表面跨膜受体家族,已经发现800多个成员,参与多种生命活动以及内分泌与代谢等多种生理过程,同时,与糖尿病、心脏病...
Human GPCR Signaling Pathway, 一、产品介绍: BioTNT qPCR Array专为检测不同组织或细胞中特定基因的表达量而设计,这些基因按照预制或定制要求成套设置。检测结果所显示的表达差异可帮助研究者鉴定或验证这些基因的
Rat GPCR Signaling Pathway, 一、产品介绍: BioTNT qPCR Array专为检测不同组织或细胞中特定基因的表达量而设计,这些基因按照预制或定制要求成套设置。检测结果所显示的表达差异可帮助研究者鉴定或验证这些基因的
Time and cost may be saved if GPCR modulators are assessed in terms of signaling pathway selectivity, species selectivity, and selectivity against closely-related family members early in the drug discovery process, perhaps even at the stage of high-throughput screening. Examples are given of how ...
aLaboratory data have shown that many interventions such as activation of GPCR, insulin, and postconditioning canprotect the heart from reperfusion injury in various experi-mental settings and animal species. The identification ofthe roles of the RISK pathway, GSK-3β, and the mPTP in prevention ...
Despite more than 800 GPCRs sharing a common architecture, unique differences govern ligand specificity and pathway selectivity. From the relatively simplified view offered by classical radioligand binding assays and contractility responses in organ baths, the road from ligand binding to biological action ...
Katanaev VL: The Wnt/Frizzled GPCR signaling pathway. Biochemistry (Mosc) 75: 1428-1434, 2010.Katanaev VL.The Wnt/Frizzled GPCR signaling pathway.Bio-Katanaev, V. L. (2010) The Wnt/Frizzled GPCR Signaling Pathway. Biochemistry 75, 1428- 1434....
Katanaev V. L. (2010). The Wnt/Frizzled GPCR signaling pathway . Biochemistry 75 , 1428-1434 10.1134/S0006297910120023 [ Cross Ref ]Katanaev, V. L. (2010). The Wnt/Frizzled GPCR signaling pathway. Biochemistry 75, 1428-1434.Katanaev, V.L. (2010). The Wnt/Frizzled GPCR signaling ...