(1999) Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells. J. Cell Biol., 147, 743±760.J. White, L. Johannes, F. Mallard, A. Girod, S. Grill, S. Reinsch, et al., Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells, J...
Consistently, we found that disrupting the secretion of human Wnt5a also induced ER stress in mammalian cells. Furthermore, we showed that a C-terminal KKVY-motif of Wg is required for its retrograde Golgi-to-ER transport, thus inducing ER stress. Next, we investigated if COPI, the ...
► ARF1 activation is involved in the EGFR transport to the ER and the nucleus. ► Assembly of γ-COP coatomer mediates EGFR transport to the ER and the nucleus. ► Golgi-to-ER retrograde trafficking regulates nuclear transport of EGFR. ...
Endocytosed Shiga toxin is transported from the Golgi complex to the endoplasmic reticulum in butyric acid-treated A431 cells. We here examine the extent of this retrograde transport and its regulation. The short B fragment of Shiga toxin is sufficient for transport to the ER. The B fragment o...
Endocytosed Shiga toxin is transported from the Golgi complex to the endoplasmic reticulum in butyric acid-treated A431 cells. We here examine the extent of this retrograde transport and its regulation. The short B fragment of Shiga toxin is sufficient for transport to the ER. The B fragment ...
PtdIns(3)P-bound UVRAG coordi- nates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex. Nat Cell Biol 2013; 15:1206-1219.He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh ...
The Golgi apparatus is the central sorting and biosynthesis hub of the secretory pathway, and uses vesicle transport for the recycling of its resident enzy
It has been generally thought that Golgi-to-ER retrograde transport of GTs is a COPI-dependent process (26, 27). However, other reports show that this process is COPI-independent (11, 28., 29., 30.). We have shown that this step is mediated by non-muscle myosin IIA (NMIIA) (30)...
The importance of endosome-to-trans-Golgi network (TGN) retrograde transport in the anterograde transport of proteins is unclear. In this study, genome-wide screening of the factors necessary for efficient anterograde protein transport in human haploid cells identified subunits of the Golgi-associated ...
associated with the microtubules,37while the TGN condenses close to the microtubule organizing center (MTOC).38,39The effects of brefeldin A on both protein transport and Golgi structure are reversible.40This retrograde transport requires energy and brefeldin A does not cause redistribution of ...