The invention relates to compositions containing an inhibitor of the Golgi enzyme 伪-mannosidase II and which may contain an interferon or interferon inducer and to the use of such compositions for the production of medicaments for use in methods of preventing and treating diseases, such as ...
Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells Rat liver alpha-mannosidase II, a hydrolase involved in the processing of asparagine-linked oligosaccharides, is an integral membrane glycoprotein facing t... van,den,Elsen,... - 《Embo Jour...
Critical steps in the N -glycan biosynthetic pathway include the trimming of glucose and mannose residues by processing α-glucosidases and α-mannosidases in the endoplasmic reticulum (ER) and Golgi complex to result in the Man 3 GlcNAc 2 core structure necessary for conversion to complex-type ...
Using the murine cDNA that encodes Golgi alpha-mannosidase II (GlcNAc transferase I-dependent alpha 1,3[alpha 1,6] mannosidase; EC 3.2.1.114) as a probe to screen a cDNA library made from Drosophila melanogaster (Dm) embryos, we have isolated GmII, the Dm sequence homologue. The 3926-bp ...
Andria, G. and Sly, W. S. 1981. Intermediate Golgi a-mannosidase activity in fibroblasts from patients with mannosidosis and mucolipidosis II and III. Pediatr. Res. 15 : 70-73.ANDRIA G, SLY WS: Intermediate Golgi a-D-mannosidase activity in fibroblasts from patients with mannosidosis ...
上海玉博生物科技有限公司 主要致力于“Rabbit polyclonal to Mannosidase II - Golgi Marker Abcam ab5822 ”的生产销售。多年的“Rabbit polyclonal to Mannosidase II - Golgi Marker Abcam ab5822 ”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司
W. Novel purification of the catalytic domain of Golgi alpha-mannosidase II. Characterization and comparison with the intact enzyme. The Journal of biological chemistry 266, 16876–16885 (1991). 61. Misago, M. et al. Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II ...
Golgi alpha-mannosidase II (GlcNAc transferase I-dependent alpha 1,3[alpha 1,6] mannosidase, EC 3.2.1.114) catalyzes the final hydrolytic step in the N-gly... K,W,Moremen,... - 《Journal of Cell Biology》 被引量: 210发表: 1991年 Mutations in the Alpha 1,2-Mannosidase Gene, MAN1B1...
The Drosophila GMII gene encodes a Golgi alpha-mannosidase II J. Cell Sci., 112 (1999), pp. 3319-3330 Google Scholar Raote and Malhotra, 2021 I. Raote, V. Malhotra Tunnels for Protein Export from the Endoplasmic Reticulum Annu. Rev. Biochem., 90 (2021), pp. 605-630 Google Scholar ...
monosaccharide residues (Fig. 1band c)10,19,20. Firstly, the high-mannoseN-glycan core is trimmed and acetylglucosamine is attached, which are catalyzed by β1,2N-acetylglucosaminyltransferase I, Golgi α-mannosidase II and β1,2N-acetylglucosaminyltransferase II sequentially, before it is ...