However, the underlying molecular mechanisms and therapeutic targets of glycolipid metabolism disorder remain to be elucidated. Progress in high-throughput technologies has helped clarify the pathophysiology of glycolipid metabolism disorder. In the present review, we explored the ways and means by which ...
In this study, we found that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure. The subcellular morphology did not show a significant change caused by HMGB1 ...
Insufficient exercise is a risk factor for developing this disorder [3]. Lack of exercise can lead to a range of health problems, such as obesity, hyperlipidaemia, increased insulin resistance, and disturbances in glucose metabolism [[4], [5], [6]]. By consensus, exercise is now listed ...
mainly manifested by the increase in triglyceride (TG) and the decrease in high-density lipoprotein cholesterol (HDL-C).Citation11The synergistic effect of glucose and lipid metabolism disorder continuously aggravates insulin resistance and accelerates...
disorder and insulin resistance in vivo and in vitro.DHEA prevented lipid metabolism disorders by enhancing phospho (p)-protein kinase AMP-activated catalytic subunit alpha (AMPKα) (Thr172) protein level and its downstream lipid metabolism-related factors in liver of rats fed an HFD or in PA-...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook glycolipid Medical Encyclopedia Wikipedia gly·co·lip·id (glī′kə-lĭp′ĭd) n. A lipid that contains one or more carbohydrate groups. American Heritage® Dictionary of the English Language, Fifth Edit...
Caloric restriction can effectively improve glucolipid metabolic disorder,and sirtuins family proteins activated in this process are important molecules affecting the glycolipid metabolism. Sirtuins are NAD-dependent deacetylases,widespread in a variety of cells,and widely involved in the metabolisms of carbo...
High doses of bisphenol AF (BPAF), a widely used chemical in many products, has been reported to exert adverse effects on lipid or glucose metabolism, but whether low-dose exposure, especially in combination with a high-sugar, high-fat diet (Western diet, WD), has unacceptable effects remai...
The gut microbiota function of the high-intensity interval exercise group seems to be more similar to that of the normal groupThe disorder of glucose and lipid metabolism in diabetes rats may be attributed to the change of intestinal flora structureThe pathways closely related to the production of...
2.2.3.2Host-pathogen interactions in glycolipid metabolism As mentioned above, acetate has been identified as an important regulator of the mevalonate pathway inB. burgdorferis.l. Interestingly, acetate has also been linked to theinflammatory responsein response toB. burgdorferis.l. infection. Additio...