This chapter discusses the recent advances in disorders of lipid metabolism. Two new hypotheses on plaque development have been proposed. Once plaque formation has been initiated, the lesion may remain fixed, regress or become a nidus for deposited cholesterol. An increase of 100 mg percent in ...
Sandhoff disease is a lipid-storage disorder caused by a defect in ganglioside metabolism. It is caused by a lack of functional N-acetyl-beta-d-glucosaminidase A and B due to mutations in the HEXB gene. Typical, early-onset Sandhoff disease presents before 9 months of age with progressive ps...
lipid metabolism disordersThe metabolic syndrome (MetS) represents a combination of cardiometabolic risk determinants including obesity (central adiposity), insulin... M. Freeman,G. Walford - 《Endocrinology Adult & Pediatric》 被引量: 13发表: 2016年 The Treatment of Disorders of Lipid Metabolism Back...
J. et al. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell 134, 97–111 (2008). An early demonstration of the importance of LXR signaling and lipid metabolism in modulating T cell expansion and acquired immunity. Article CAS PubMed PubMed Central ...
The intimate association between hypercholesterolemia and atherosclerosis has been known since Anitschkow published the results of his research in 1913 (1). However, the therapeutic potential of this connection has become fully apparent only in the...Deutsches Aerzteblatt InternationalDeutscher Ärzte...
Our studies suggested that MTP may be associated with the lipid metabolism disorder in OLETF rats and metformin could improve lipid metabolism through reducing the expression of MTP. 展开 关键词: Microsomal triglyceride transfer protein Hypertriglyceridemia Type 2 diabetes mellitus Insulin-resistant Otsuka ...
Keywords: DEHP, TYK2, STAT1, High-fat diet, Autophagy, Lipid metabolism INTRODUCTION Di (2-ethylhexyl) phthalate (DEHP) is one of the most common endocrine disruptor substances (EDS). DEHP is a plasticizer, which is most frequently detected in a variety of products and applications such as...
Peroxisomes, lipid metabolism and lipotoxicity Biochim. Biophys. Acta, 1801 (2010), pp. 272-280 View PDFView articleView in ScopusGoogle Scholar [9] P.P. Van Veldhoven Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism J. Lipid Res., 51 (2010), pp. 2863-...
Shiau HJ, Aichelmann-Reidy ME, Reynolds MA, Influence of sex steroids on inflammation and bone metabolism. Periodontol 2000. 2014;64:81–94. Article PubMed Google Scholar Trigunaite A, Dimo J, Jørgensen TN. Suppressive effects of androgens on the immune system. Cell Immunol. 2015;294:87...
Hitherto diphenylazetid ions, methods for their preparation, drugs containing these compounds and their use in the treatment of lipid metabolism disorders 来自 掌桥科研 喜欢 0 阅读量: 14 申请(专利)号: DK20010271353T 申请日期: 2001-12-11