This lipid disorder consists of elevations of serum triglycerides, apolipoprotein B (apo B) and small (LDL) particles, and low levels of HDL [1]. It can be differentiated from elevated LDL cholesterol, which is the major lipid risk factor for CVD. Many controlled clinical trials show that LD...
Changes in lipid metabolism are closely related to renal fibrosis. FAO is the optimal energy supply mode for renal cellular activity, and most fatty acids are generated via FAO, producing adenosine triphosphate (ATP) to supply energy to TECs. In contrast, uncatabolized fatty acids are typically ...
What is fluvoxamine's only FDA-approved indication? a. Major depressive disorder b. Post-traumatic stress disorder c. Obsessive-compulsive disorder d. Social anxiety disorder How is energy from the metabolism of a Cheeto used in a human body?
Fat metabolism: When fat is metabolized in the body it forms products known as ketone bodies. A high amount of ketone bodies in the blood or urine can be indicative of a health disorder as glucose is not being oxidized as it should for ...
“first-hit”, linked to obesity, insulin resistance and metabolic syndrome, while the “second-hit” is activated by hepatic inflammation, together with oxidative stress and endotoxemia, which have a key role in the progression to non-alcoholic steatohepatitis (NASH) and, over time, to fibrosis...
Hemp has such a long, diverse, and compelling history that it boggles the mind. Hemp has been grown in almost every corner of the earth. Hemp has left a legacy even in places where it is currently, temporarily illegal (the illegalization of hemp is very recent in the larger picture of ...
A most typical Inherited metabolic disorder (IMD) is the Maple Syrup Urine Disease (MSUD). Maple syrup urine disease (MSUD) is a rare autosomal recessive inherited disorder. The overall incidence in the United States is approximately 1/185,000, but in areas with high rates of consanguineous ma...
The missense mutations, frequently clustered in the GTPase domain and assumed to exert a dominant-negative effect, are in most cases associated with the severe multisystem disorder recognized as DOA “plus”. This is characterized by a multi-systemic involvement, associated with a large spectrum of...
High blood pressure (hypertension) is a common medical disorder that increases the risk of heart disease, stroke, and kidney disorders. It is one of the most important causes of premature death worldwide (31). Animal and human studies suggest that intermittent fasting lowers blood pressure (32,...
It is well established that second-generation antipsychotics are associated with a greater alteration of lipid metabolism, although the exact mechanism has not been clarified yet. Recently, a key role for gut microbiota and composition of the intestinal microflora has been proposed, but it requires ...