insulin binding to its receptors leads to enhanced glucose transport into skeletal muscle, adipose tissue, and the heart, mainly facilitated by an acute translocation of GLUT4 transporter vesicles to the plasma membrane and, in addition, to an inhibition of hepatic gluconeogenesis...
However, glucose oxidase (GOD), which has been used as an EBFC anode enzyme, revealed extreme cytotoxicity (~10%) due to the lethal concentration of H2O2 byproducts (~1500 µM). Therefore, with its cytocompatibility and cell-stimulating effects, the GDH-based EBFC is considered a ...
BPE is performed to derive both of cathode and anode electrodes for the development of mediatorless/membraneless biofuel cell (BFC). On one hand, a preferable substrate for immobilization of bilirubin oxidase enzyme
Highly oriented ZnO nanorod (NR) arrays were fabricated on a seeded substrate through a hydrothermal route. The prepared ZnO nanorods were used as an amperometric enzyme electrode, in which glucose oxidase (GOx) was immobilised through physical adsorption. The modified electrode was designated as Nafi...
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glucose oxidase; glucose; stability; protein engineering; disulfide bond; mutagenesis; Aspergillus niger; in silico study1. Introduction Glucose oxidase (GOx; Enzyme Commission Number: 1.1.3.4) is an enzyme found in several natural sources, including insects, fruits, and fungi. GOx is widely ...
(CVD). An important action to consider is that UA is an outcome of xanthine oxidoreductase (XOR) activity, which is a significant contributor to ROS and oxidative stress. Additionally, XOR is closely connected to nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which also produces ROS ...
Furthermore, heat-killed Bifidobacterium breve B-3 intake significantly promoted skeletal muscle mass and function with mitochondrial biogenesis by increasing phosphorylation of AMPK and activation of PGC-1α and cytochrome c oxidase in the rat soleus [117]. Administering the probiotic, Lactobacillus ...