Lam CW,But WM,Shek CC,et al.Glucose-6-phosphatase gene (727GT) splicing mutation is prevalent in Hong Kong Chinese patients with glycogen storage disease type 1a. Clinical Genetics . 1998Lam C-W, But W-M, Shek C-C, Tong S-F, Chan Y-S, Choy K-W, Tse W-Y, Pang C-P, ...
Parvari R , Lei, K-J , Szonyi L , Narkis G , Moses S , Chou JY . 1997b . Two new mutations in the glucose-6-phosphatase gene cause glycogen storage disease in Hungarian patients . Eur J Hum Genet 5 : 191 – 195 .Parvari R, Lei K-J, Szonyi L, Narkis G, Moses S, Chou...
Mutations in the glucose-6-phosphatase gene that cause glycogen storage disease type 1a Glycogen storage disease (GSD) type 1a is caused by the deficiency of D-glucose-6-phosphatase (G6Pase), the key enzyme in glucose homeostasis. Despite both... K Lei,L Shelly,C Pan,... - 《Science》...
(redirected fromglucose-6-phosphatase) Thesaurus Medical Encyclopedia Related to glucose-6-phosphatase:glucose-6-phosphate dehydrogenase glu·cose (glo͞o′kōs′) n. 1.A monosaccharide sugar, C6H12O6, that is used by living things to obtain energy through the process of aerobic respiration within...
Glucose-6-phosphatase plays an important role in the regulation of hepatic glucose production, and insulin suppresses glucose-6-phosphatase gene expression. Recent studies indicate that protein kinase B and Forkhead proteins contribute to insulin-regulated gene expression in the liver. Here, we examined...
6Kinderklinik der Universita¨t Du¨ sseldorf, Germany The purpose of this work was to test the hypothesis that mutations in the putative glucose 6-phosphate translocase gene would account for most of the cases of GSD I that are not explained by mutations in the phosphohydrolase gene, ie ...
Glucose-6-phosphatase plays an important role in the regulation of hepatic glucose production, and insulin suppresses glucose-6-phosphatase gene expression. Recent studies indicate that protein kinase B and Forkhead proteins contribute to insulin-regulated gene expression in the liver. Here, we examined...
The multicomponent hepatic glucose 6-phosphatase (Glc-6-Pase) system catalyzes the terminal step of hepatic glucose production and plays a key role in the regulation of blood glucose. We used the chlorogenic acid derivative S 3483, a reversible inhibitor of the glucose-6-phosphate (Glc-6-P) ...
Normalization of the plasma glucose concentration in diabetic rats with either insulin or the glycosuric agent phlorizin normalized the hepatic glucose-6-phosphatase messenger RNA and protein within approximately 8 h. Conversely, phlorizin failed to decrease hepatic glucose-6-phosphatase gene expression in...
GLUCOSE-6-PHOSPHATASE IN PANCREATIC β-CELL METABOLISM* I.-B.TÄLJEDAL, inThe Structure and Metabolism of the Pancreatic Islets, 1970 MODELS OF GLUCOSE-6-PHOSPHATE METABOLISM IN β-CELL In discussing what role may be envisaged for islet glucose-6-phosphatase, it must first be emphasized that ...