应用领域:Cre工具鼠,Glp1r-IRES-Cre小鼠与含有loxP侧翼序列的小鼠交配时,Cre介导的重组将导致后代表达Cre细胞中floxed 序列的缺失。GLP1R 是存在于许多细胞类型上的受体,包括胰腺 β 细胞、中枢神经系统中的神经元亚群,也投射到胃肠道。 *使用本品系发表的文献需注明: Glp1r-IRES-Cre mice (Cat. NO. NM-KI-20...
a, Representative image and quantification of viral expression (EGFP) in Glp1r-expessing neurons ofGlp1r-ires-Cremice (RNAin situhybridization).b, Representative images of Glp1r expression (RNAin situhybridization) in the DVC, ARC, and NG of control mice or mice with GLP1R neuron ablation in...
a, Coronal images of soma-restricted AAV5-EF1a-DIO-EGFPL10a in the DVC of Glp1r-ires-Cre mice across the rostral-caudal axis. Scale bar, 100 µm. b, Quantification of GLP1R neurons in AP and NTS across the rostral-caudal axis (n = 3 mice/group). c, Coronal images of so...
These mice express Cre-recombinase under the Glp1r promoter [30] (MGI ID: 5755096). Two knock-in Glp1rCre models exist with IRES-Cre knocked-in downstream of the Glp1r gene (i.e. after the stop codon) [31, 55] (JAX stock no. 029283). Following breeding with animals possessing LoxP...
应用领域:Cre工具鼠,Glp1r-IRES-Cre小鼠与含有loxP侧翼序列的小鼠交配时,Cre介导的重组将导致后代表达Cre细胞中floxed 序列的缺失。GLP1R 是存在于许多细胞类型上的受体,包括胰腺 β 细胞、中枢神经系统中的神经元亚群,也投射到胃肠道。 *使用本品系发表的文献需注明: Glp1r-IRES-Cre mice (Cat. NO. NM-KI-20...
Glp1r-IRES-Cre 品系名:C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc 品系状态:活体 | 目录号:NM-KI-200134 hGLP1R 品系名:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc 品系状态:活体 | 目录号:NM-HU-200220 hGCGR/hGLP1R 品系名:C57BL/6Smoc-Gcgrem(hGCGR)Glp1rem2(hGLP1R)Smoc 品系状态:活体 | 目录号:NM-...
Glp1r-IRES-Cre 品系名:C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc 品系状态:活体 | 目录号:NM-KI-200134 hGLP1R 品系名:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc 品系状态:活体 | 目录号:NM-HU-200220 hGCGR/hGLP1R 品系名:C57BL/6Smoc-Gcgrem(hGCGR)Glp1rem2(hGLP1R)Smoc 品系状态:活体 | 目录号:NM-...
敲除Glp1r基因exon 2,建立Glp1r基因敲除小鼠模型。 应用领域:II型糖尿病相关 *使用本品系发表的文献需注明: Glp1r-KO mice (Cat. NO. NM-KO-190803) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Fig.1 Detection of Glp1r expression in lung by RT-PCR. ...