Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL. GLP-1R抗体 GLP1R Recombinant Monoclonal Antibody (Active)(Code: CSB-RA009514MA1HU) 参考文献: [1] Malm-Erjefält, Monika, et al. "Metabolism and excretion...
Life Sci Human gestational diabetes mellitus-derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets mouseWB Biomed Pharmacother Liraglutide, a glucagon-like peptide-1 receptor agonist, suppresses osteoclastogenesis through the inhibition of NF-κB an...
This reporter cell was incubated with serial dilutions of Tirzepatide (a dual GLP-1R and GIPR agonist). The EC50 of Tirzepatide was approximately 0.042 nM. This reporter cell was incubated with serial dilutions of Tirzepatide (a dual GLP-1R and GIPR agonist). The max induction fold was ...
然后点右上角“…”菜单,选择“设为星标” 编者按:GLP-1自发现以来,已然成为一种“多面手”激素——其接二连三的代谢功能被人们发现,远远超出了作为肠促胰素的经典定义。GLP-1众多有益的作用使其受体激动剂逐渐成为更多新兴的...
Glutazumab is potentially to be developed as a bi-weekly/monthly dosing GLP-1R agonist product for the type II diabetes and obesity. About Gmax Biopharm Gmax Biopharm is one of the top innovative GPCR antibody companies, focusing on the new antibody therapeutics development for cardiovascular ...
This is particularly the case in the brain, where robust counter-staining methods (antibody, probe) work less effectively and RNAscope or similar approaches are needed. 6. Fluorescent agonist/antagonist probes Current GLP1R antibodies have variable specificity and, except for the monoclonal ...
This reporter cell was incubated with serial dilutions of Tirzepatide (a dual GLP-1R and GIPR agonist). The max induction fold was approximately 328. ACROBiosystems百普赛斯全面助力抗体药物研发,在原有的靶点蛋白业务基础上推出了以:ADCC及ADCP功能验证用报告基因细胞系、靶点及通路研究、Cross-linking药物...
GLP-1R agonist 3 是一种有效的 GLP-1R 激动剂。GLP-1R agonist 3 是一种增稠的咪唑衍生物化合物。胰高血糖素样肽-1 (GLP-1) 是一种由下消化道 L 细胞分泌的肠道降血糖激素。GLP-1R agonist 3 具有糖尿病研究潜力 (摘自专利 WO2021197464A1,化合物 1)。 产品介绍 GLP-1R agonist 3 是一种有效的 GL...
The present invention provides GA targeting compounds which comprise GA targeting agent-linker conjugates linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.カート ブラッドショー...
These two different results may have been caused by the different sizes and specificities of the amplification primers and different antibody types used. In the current work, to confirm the presence of GLP-1R on the surface of osteoclasts, we detected the gene and protein levels of GLP-1R ...