Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL.GLP-1R抗体 GLP1R Recombinant Monoclonal Antibody (Active)(Code: CSB-RA009514MA1HU)参考文献:[1] Malm-Erjefält, Monika, et al. "Metabolism and excretio...
AMG 133 (maridebart cafraglutide) is a bispecific molecule engineered by conjugating a fully human monoclonal anti-human GIPR antagonist antibody to two GLP-1 analogue agonist peptides using amino acid linkers. 双靶点作用机制: GIPR拮抗:通过抑制GIPR信号,MariTide减少了GIP对胰岛素分泌的增强效应,同时...
临床前数据表明,相较于单独GLP-1类似物或单独雌激素,GLP-1/雌激素结合产物可增强小鼠厌食、减重、促胰岛素和胰岛保存作用[83-85]。而这种GLP-1/雌激素结合物并没有雌激素独有的促子宫内膜增生的效应,仅体现GLP-1成分介导的治疗指标改善。GLP-1R靶向作用也...
产品类型 Antibody 全称 glucagon-like peptide 1 receptor 别名 GLP-1-R, GLP-1R, GLP-1 receptor, GLP 1R, GLP 1 receptor 计算分子量 463 aa, 53 kDa 观测分子量 53 kDa GenBank蛋白编号 BC112126 基因名称 GLP1R Gene ID (NCBI) 2740 RRID AB_2880421 偶联类型 Unconjugated 形式 Liquid 纯化方式 ...
Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL. GLP-1R抗体 GLP1R Recombinant Monoclonal Antibody (Active)(Code: CSB-RA009514MA1HU) 参考文献: [1] Malm-Erjefält, Monika, et al. "Metabolism and excretion...
[12]Noyan-Ashraf, M.H., Momen, M.A., Ban, K., Sadi, A.M., Zhou, Y.Q., Riazi, A.M., et al. 2009. GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardi...
GLP‑1 receptor agonist protects palmitate-induced insulin resistance in skeletal muscle cells by up-regulating sestrin2 to promote autophagyXue Tian, Yu Gao, Mowei Kong, Lihua Zhao, Enhong Xing, Qitian Sun, Jianqiu He, Yanan Lu & Zengbin Feng ...
No. CHEK-ATF096) or negative control cell using PE-labeled anti-human GLP-1R antibody. ✍ GLP-1R激动剂筛选应用案例 This reporter cell was incubated with serial dilutions of Tirzepatide (a dual GLP-1R and GIPR agonist). The EC50 of Tirzepatide was approximately 0.83 nM. This reporter ...
Description:Bofanglutide是一种类胰高血糖素肽 1 (GLP-1) 受体激动剂多肽,是由31个氨基酸组成的多肽。 Bofanglutide is a glucagon peptide-1 (GLP-1) receptor agonist peptide composed of 31 amino acids. Purity (HPLC) ≥98.0% Single impurity≤2% Peptide content≥75.0% Amino Acid Composition≤±15...
名称:Anti-Semaglutide (GLP-1 analogue) Polyclonal antibody抗体 别名:Sermaglutide, Semaglutide fandachem, Semaglutide impurity, Sermaglutide USP/EP/BP, semaglutide, Sermaglutide 货号:PHK13901 宿主:Rabbit 适用物种:Human 免疫原:Synthesized Semaglutide (GLP-1 analogue) conjugated with Carrier protein. ...