[72] Gault, V.A., Bhat, V.K., Irwin, N., Flatt, P.R. 2013. A novel glucagon-like peptide-1 (GLP- 1)/glucagon hybrid peptide with triple-acting agonist activity at glucose-dependent insulinotropic polypeptide, GLP-1, and glucagon ...
根据安进科学家发表的论文《Chronic glucose-dependent insulinotropic polypeptide receptor(GIPR)agonism desensitizes adipocyte GIPR activity mimicking functional GIP antagonism》阐述的机制,长期的GIPR刺激可以导致GIPR脱敏,不再响应后续的GIP刺激,从而最终实质上发挥了拮抗作用,此外,可能的易内吞效应也会导致其事实上...
Glp-1 activity enhancerPROBLEM TO BE SOLVED: To provide a GLP-1 activity enhancer which is efficacious, and high in the safety, and also ingestible continuously. SOLUTION: This GLP-1 activity enhancer contains as an effective component an extract from a plant selected from among Salacia ...
根据安进科学家发表的论文《Chronic glucose-dependent insulinotropic polypeptide receptor(GIPR)agonism desensitizes adipocyte GIPR activity mimicking functional GIP antagonism》阐述的机制,长期的GIPR刺激可以导致GIPR脱敏,不再响应后续的GIP刺激,从而最终实质上发挥了拮抗作用,此外,可能的易内吞效应也会导致其事实上拮抗...
[9] Shousha, S., Nakahara, K., Nasu, T., Sakamoto, T., Murakami, N. 2007. Effect of glucagon-like peptide-1 and -2 on regulation of food intake, body temperature and locomotor activity in the Japanese quail. Neurosci Lett 415:102-107. ...
[9] Shousha, S., Nakahara, K., Nasu, T., Sakamoto, T., Murakami, N. 2007. Effect of glucagon-like peptide-1 and -2 on regulation of food intake, body temperature and locomotor activity in the Japanese quail. Neurosci Lett 415:102-107. ...
根据安进科学家发表的论文《Chronic glucose-dependent insulinotropic polypeptide receptor(GIPR)agonism desensitizes adipocyte GIPR activity mimicking functional GIP antagonism》阐述的机制,长期的GIPR刺激可以导致GIPR脱敏,不再响应后续的GIP刺激,从而最终实质上发挥了拮抗作用,此外,...
[24] Mochida, T., Hira, T., Hara, H. 2010. The corn protein, zein hydrolysate, administered into the ileum attenuates hyperglycemia via its dual action on glucagon-like peptide-1 secretion and dipeptidyl peptidase-IV activity in rats. Endocrinology 151:3095-3104. ...
[72] Gault, V.A., Bhat, V.K., Irwin, N., Flatt, P.R. 2013. A novel glucagon-like peptide-1 (GLP- 1)/glucagon hybrid peptide with triple-acting agonist activity at glucose-dependent insulinotropic polypeptide, GLP-1, and glucagon receptors and therapeutic potential in high fat-fed mic...
[24] Mochida, T., Hira, T., Hara, H. 2010. The corn protein, zein hydrolysate, administered into the ileum attenuates hyperglycemia via its dual action on glucagon-like peptide-1 secretion and dipeptidyl peptidase-...