GLP-1 RAs在超重/肥胖和糖尿病之间的重叠使用,以及社交媒体上关于公众化的美丽体型趋势,导致了GLP-1 RAs使用的“大流行增加”。GLP-1 RAs是一类控制GLP-1(一种在饭后由肠道释放的天然肠促胰岛素激素)作用的药物。GLP-1 RAs对代谢...
This large multinational study looked at the use and safety of GLP-1 receptor agonists and other noninsulin ADMs early in pregnancy in comparison to insulin.C.E. CestaR. RotemB.T. BatemanC. GabrielJ.M. CohenK. FuruM. GisslerK.F. Huybrechts...
Ok! Considerations for anesthesia care in relation to use of glucagon-like peptide-1 (GLP-1) receptor agonists before surgery are addressed in a report published March 11 by the American Association of Nurse Anesthesiology (AANA). Ad AANA developed policies and procedures that align with best ava...
Drugs like Ozempic, Wegovy and Mounjaro have been around for years, but they've recently been making headlines due to a rise in popularity as weight loss agents. They all belong to a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1RAs), which mimic a hormone (GL...
Regurgitation under anesthesia in a fasted patient prescribed semaglutide for weight loss: a case report. PMID: 37280458 Glucagon-like peptide-1 receptor agonists in type 2 diabetes treatment: are they all the same? PMID: 30156747 A new era for oral peptides: SNAC and the development of oral...
Pulmonary Aspiration During General Anesthesia or Deep Sedation: RYBELSUS® delays gastric emptying. There have been rare postmarketing reports of pulmonary aspiration in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation who ...
Patients taking either of these glucagon-like peptide-1 (GLP-1) receptor agonists had nine times an elevated risk for pancreatitis. They were also four times more likely to develop bowel obstruction and over 3.5 times more likely to experience gastroparesis. ...
GlP-1 receptor agonists are a class of medications that are becoming increasingly popular. Large trials have shown that their use provides reliable weight loss in obese patients and improved glycemic control in diabetic patients. Its use also has broader implications for overall metabolic health and ...
Most patients may continue to safely take glucagon-like peptide-1 (GLP-1) receptor agonists as prescribed before undergoing elective surgery and gastrointestinal endoscopies, according to new clinical guidance released by five surgical and medical societies including the American Society for Metabolic and...
receptor binding kinetics and β-arrestin-biased signaling in the observed trafficking profiles, identifying a linked set of agonist characteristics optimally suited for insulin secretion, not shared by GLP-1R agonists in the current clinical use. We find that β-arrestin recruitment to GLP-1Rs ...