Healthcare providersprescribeGLP-1 agonists for two conditions: Type 2 diabetes and obesity. prescribe:开药 GLP-1 agonists for Type 2 diabetes The FDA approves the use of GLP-1 agonists to help manage Type 2 diabetes (T2D). This is because GlP-1 agonists help lower blood sugar levels. The...
3.Novo's GLP-1 liraglutide may protect brain from Alzheimer's, new study finds.By Darren Incorvaia Jul 30, 2024 4.The mechanism and efficacy of GLP-1 receptor agonists in the treatment of Alzheimer’s disease 5.12-month neuro...
43.https://www.wsj.com/video/series/daniela-hernandez/the-science-behind-new-weight-loss-drugs-like-ozempic/532CB84C-13A6-4E3B-AB5B-837713CC42E1 44.https://www.goodrx.com/classes/glp-1-agonists/glp-1-drugs-comparison
^Sodhi M, Rezaeianzadeh R, Kezouh A, Etminan M. Risk of Gastrointestinal Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss. JAMA. 2023 Nov 14;330(18):1795-1797.
其全称为Glucagon-like peptide-1 receptor agonists, GLP-1RA，也就是GLP-1胰高血糖素样肽-1受体。2022年，GLP-1市场规模超过胰岛素，领跑整个糖尿病治疗市场。一个数据证明是，使用GLP-1类药物的糖尿病患者比重只有9%，但却贡献了31%的市场份额。不过，因为它需要刺激胰岛素分泌才能起效，因此对胰岛功能完全失效...
GLP-1 agonists are medications that primarily help manage blood sugar levels in individuals with Type 2 diabetes. Some variants also assist in weight loss. These are injectable medications, administered under the skin with a syringe. Common injection sites include the abdomen, thighs, ...
最新的抗肥胖药物靶向GLP-1受体,胰高血糖素样肽-1 受体(GLP1R)是一种在胰腺 β 细胞和大脑神经元上发现的受体蛋白,它通过增强胰岛素分泌参与控制血糖水平。 胰高血糖素样肽1受体激动剂(GLP-1 receptor agonists, 简称GLP-1肽),通过增强β胰腺细胞分泌胰岛素和抑制α胰腺细胞释放胰高血糖素来改善血糖控制。[5]...
通过AI查询，有一篇来自今年在《糖尿病护理》杂志上发表的研究《GLP-1 Receptor Agonists and the Risk of Thyroid Cancer》与EMA的主题相关。该项研究的研究者利用法国国家健康保险系统（SNDS）数据库对相关病例进行了回顾性对照分析，研究对象包括2006年至2018年间接受二线抗糖尿病药物治疗的2型糖尿病患者。所有的...
最新的抗肥胖药物靶向GLP-1受体,胰高血糖素样肽-1 受体(GLP1R)是一种在胰腺 β 细胞和大脑神经元上发现的受体蛋白,它通过增强胰岛素分泌参与控制血糖水平。 胰高血糖素样肽1受体激动剂(GLP-1 receptor agonists, 简称GLP-1肽),通过增强β胰腺细胞分泌胰岛素和抑制α胰腺细胞释放胰高血糖素来改善血糖控制。[5]...
胰高糖素样肽-1受体激动剂(glucagon-like peptide-1 receptor agonists ,GLP-1RA)与体内天然GLP-1的氨基酸序列部分或完全同源,具备同样的生物活性,且不容易被酶降解、作用维持时间明显延长,能够较好地满足临床治疗需要,已成为近年的新型降糖与减肥药。 图1.GLP-1工作机制 来源:国金证券...