[16] Arakawa, M., Ebato, C., Mita, T., Hirose, T., Kawamori, R., Fujitani, Y., et al. 2009. Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. Biochem Biophys Res Commun 390:809-...
Fujitani, Y., et al. 2009. Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. Biochem Biophys Res Commun 390:809-814.
Fujitani, Y., et al. 2009. Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. Biochem Biophys Res Commun 390:809-814.
and reagent for carbohydrate conversion technology”in carbohydrates as organic raw materials,247-265(f.w.lichtenthaler编撰)vch publishers,new york(1991);ferenci,t.,j.bacteriol,144:7-11(1980)合成);烷基硫代葡萄糖苷,例如庚基-或辛基-1-硫代α-或β-d-吡喃葡萄糖苷(anatrace公司,maumee,ohio;参见sait...
改进的GLP-1受体激动剂的药物制剂.pdf,本发明涉及固体口服药物组合物,其包含(i)包含GLP‑1受体激动剂的核心和(ii)第一包衣,其中第一包衣包含共聚物(A)与共聚物(B)和/或共聚物(C)和/或共聚物(D)的组合。(19)国家知识产权局 (12)发明专利申请 (10)申请公布号 CN 116419750
15b–e). The restoration of blood lipids and transaminases indicated that intestinal Nogo-B knockout restored the balance of glycolipid conversion and improved liver injury (Supplementary Information: Table S3). Metabolic cage analysis revealed that the STZ-NVK group had higher RER, energy ...
The albumin ligand modified GLP-1 analogs Rhein-C12-GLP-1 did not reduce cell viability treated with 1000 nM and also did not elevate either the AST or ALT level administrated with a high dose of 500 mg·kg−1. The Rhein-C12-GLP-1 can effectively decrease fasting blood glucose and ...
GLP1-RAs are primarily eliminated by the kidney. Dosing adjustments of GLP1-RAs are unnecessary due to hepatic or mild renal impairment. However, patients with moderate renal impairment should avoid weekly exenatide, and dose escalations should be carefully evaluated in patients using twice-daily exe...
Human GLP-1R (Gs-coupled) cell-based agonist-activated internalization assays were performed by Eurofins Discovery. Dose–response assays (30 pM–1 µM) were performed in duplicate with Ex-4 as a positive control. Internalization of Y2-R ...
Also, in parallel studies within this experiment a lack of synbiotic-induced changes on breeding parameters was observed, as calculated for the whole period from days 1 to 41 [25]. Neither body weight gain nor feed intake, feed conversion efficiency or mortality differed significantly between ...