2. Hyperintense white-matter foci in the elderly Six lesions were infarctions, two were small foci of gliosis or noncavitated infarcts, two were plaques of demyelination, one was a minute brain cyst, and one was a congenital diverticulum of the lateral ventricle; in three foci ... Braff...
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletiondoi:10.1186/s40478-024-01734-xDeposition of amyloid beta (Aβ) into plaques is a major hallmark of Alzheimer's disease (AD). Different amyloid precursor protein ...
The oligodendroglial reaction to brain stab wounds: an immunohistochemical study. Myelin/oligodendrocyte specific protein was compared to glial fibrillary acidic protein and 2′3′-cyclic nucleotide 3′-phosphodiesterase expression in no... D Xie,RL Schultz,EF Whitter - 《Journal of Neurocytology》 ...
There were some studies showing that a certain number of BMDSCs marked with Y chromosome and GFP gene and grafted through the vein of the host animals could be presented in their brain tissue and these migrated cells expressed the specific markers forglial and neuronal cells. ...
Animal data show that high doses of the stimulant drug methamphetamine can damage brain dopamine neurones; however, it is still uncertain whether methamphetamine, at any dose, is neurotoxic to human brain. Since gliosis is typically associated with brain damage and is observed in animal models ...
Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease During physiological and pathological brain aging, important changes in the expression of peroxisome-related proteins, also correlating with ongoing gliosis, ... F Fanelli,S Sepe,M D’Amelio…...
Here we have studied the effects of a humanized APOEε4 liver[6] on synaptic integrity, insulin signaling and gliosis in a mouse model that reproduces the human plasma profile and that retains its endogenous apoE expression in the brain. Tissue samples from the cortex, hippocampus, cerebellum...
The histopathology of the condition is described. Although they appeared to originate from inflammatory foci, the tumors resembled gemistocytic fibrillary astrocytoma. Etiology was not determined, but the possible association of these tumors with toxoplasmosis and the cocarcinogenic effect of disease and ...
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by glia over-proliferation, neuro-inflammation, perturbed neural circuitry, and gastrointestinal symptoms. The role of gut dys-biosis in ASD is intriguing and should be elucida
The salience network (SN) comprises brain regions that evaluate cues in the external environment in light of internal signals. We examined the SN response to meal intake and potential genetic and acquired influences on SN function. Subjects/Methods Monozygotic (MZ; 40 pairs) and dizygotic (15 pai...