The end-of-life (EoL) phase of care is inevitable for glioblastoma (GBM) patients; however, it lacks standardization. This study aimed to characterize the utilization of care at EoL in GBM patients, focusing on trends over time, regional variability, and the influence of socioeconomic factors....
37% were hospitalized in the last month of life for an average of 9 days. Of the Gilchrist Services patients, the median length of stay in hospice was 21 days and 64% of these patients died in their residence with hospice services. Documentation of palliative care and end-of-life measures...
In the last phase, symptoms from , , decrease of vigilance, , and were the prominent clinical features. Our study demonstrates that the end of life in patients with has several periods with different clinical aspects with respect to symptoms and treatment. 展开 关键词: AED;Glioblastoma DOI:...
Seizures: If oral administration of antiepileptic drugs is not an option, intranasal midazolam and buccal clonazepam are a feasible way to treat seizures in the end-of-life phase, when patients often have difficulty swallowing. Venous thromboembolism (VTE): VTE prophylaxis with low molecular weight...
The reported quality of life of caregivers was low and in accordance with the quality of life that they attributed to the patient. Symptoms of burnout and feelings of insufficient information emphasize the urgent need for psychological support and training dedicated to caregivers. The end-of-life ...
which provides comfort at the end of life. Instead, palliative care provides you with medications and other treatments for comfort, to manage side effects of your cancer treatment, and improve your quality of life.Palliative carealso includes taking care of the emotions you may be dealing with....
Use of the GliaSite has yielded significant improvements in quality of life and tumor control.302,303 GliaSite was taken off the market for several years but was recently reintroduced, and the introduction of a new liquid form of cesium-131 is planned. Another means of increasing dose to ...
4d) or astro-mesenchymal signatures (e.g., CD44, GFAP, AQP4) were found at either end of DC2; cancer cells expressing a neuronal signature (e.g., STMN2, DLX2) were found at the end of DC1; and cancer cells expressing a GPC signature (e.g., OLIG2, NES ASCL1, HES6) were ...
Alexa Fluor 488 Donkey anti-Rabbit IgG Life Technologies Cat#A-21206; RRID:AB_2535792 Anti-rabbit IgG, HRP-linked Antibody Cell Signaling Technologies Cat#7074; RRID:AB_2099233 Biological Samples Human primary GBM sections The Brain Tumor and Neuro-Oncology Centers at the Case Western Reserve Univ...
Given that cancer patients constitute the largest population of immunocompromised individuals, it is essential to understand the impact of HCMV reactivation on GBM disease progression and quality of life. The substantial burden of clinically-relevant virus reactivation among HCMV-positive GBM patients ...