Glioblastoma (GBM) is a universally fatal disease, complicated by significant cognitive and physical disabilities, inherent to the disease course. The purpose of this study was to retrospectively analyze end-of-life care for GBM patients at an academic center and compare utilization of these services...
End-of-life care for glioblastoma multiforme patients at an academic institution 202 Background: End of life care for glioblastoma patients has not been studied in the United States. We studied 100 patients with GBM to examine use of advance directives (AD), symptom assessments, hospitalizations,...
a】Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy. 】免疫反应在有最近被诊断的glioblastoma multiforme的病人对待了以intranodal autologous肿瘤lysate树状细胞接种在辐射化疗以后。[translate]...
My guestBenjamin Kintischis a cantor, hospice and eldercare chaplain, music teacher, and the creator ofLife Review: The Hospice Musical. Ben and I are teaming up for a new series onDeath & Grief in Pop Cultureto talk about all the interesting ways death shows up in culture, what we mig...
The implications of these findings for the management of patients are readily apparent, pinpointing previously unappreciated diagnostic and therapeutic targets. In this Review, we summarize the 'explosion' of data emerging from the application of modern genomics to medulloblastoma, and in particular the ...
Currently, the SEER program covers approximately half of the total cancer patients in the US. A growing number of clinical studies have applied the SEER database in various aspects. However, the intrinsic features of the SEER database, such as the huge data volume and complexity of data types...
However, prognosis of advanced-stage patients is still poor due to the development of resistance to currently available standard therapies. Therefore, new therapeutic approaches are urgently needed. The idea to utilize the patients’ immune system to fight tumors has revolutionized the field of ...
This indicates the use of suture made from biomateri- als can significantly reduce the incidence of wound-related complications, which is beneficial for the postoperative recovery and following radiotherapy in glioma patients. Although the present study, as well as other studies, dem- onstrates that...
Specifically, for the anatomical location of brain, we have applied GaNDLF on 3D MRIs of patients diagnosed withde novoglioblastoma, to predict the EGFRvIII mutation status. The inputs for model training were structural MRI scans in tandem (passing all the scans together at once) to a VGG11 ...
Vorasidenib(AG-881) monotherapy elicited a statistically significant and clinically meaningful improvement in progression-free survival (PFS) compared with placebo in patients with residual or recurrent IDH1/2-mutant low-grade glioma, meeting the primary end point of the phase 3 INDIGO trial (NCT04164...