Glioblastoma (GBM) develops in the complex tumor microenvironment (TME) of the brain. The GBM TME consists of extracellular matrix (ECM), interstitial fluid, and non-neoplastic cells, including both immune and non-immune cells that are compartmentalized in anatomically-distinct regions referred to as...
Glioblastoma (GBM) develops in the complex tumor microenvironment (TME) of the brain. The GBM TME consists of extracellular matrix (ECM), interstitial fluid, and non-neoplastic cells, including both immune and non-immune cells that are compartmentalized in anatomically-distinct regions referred to as...
in in vitro experiments, to separate effects, check new scientific hypotheses, quantify the effect of each parameter or predict the outcome inwhat ifsituations. To overcome this limitation, a good possibility is combining the potential of new in vitro assays with the quantitative power and versatili...
One of the technicians gave us a sample of the plastic that was heated up so that Amber (and us) knew what to expect. And quite honestly, when she gave me my little piece, oh man was that sucker hot! I’m thinking to myself, how is Amber going to be able to lay there with ...
Novel therapeutic modalities using medical devices have the potential to deliver effective treatment against the most aggressive form of primary brain tumour, Glioblastoma, for which there is currently no cure. These devices not only offer methods to enhance the effect of currently available therapies ...
Using R version 4.1.1, specifically the pwr package for power analysis [15,16], we estimate that a sample of 42 MRIs is adequate to provide 80% power. In our work, we are interested in testing our AI on both pre- and post-operative MRIs. We expect at least a third of the ...
Int6 Inhibition Induces Cell Cycle Arrest and G0 Transition In order to explain the decreased proliferation with Int6 inhibition, we first looked at cell cycle and cell cycle arrest in human GBM cells. Using PI/Ki67 staining and flow cytometry, we analyzed cell cycle and cells in G0. We ...