While through the years brain research has focused on neurons, it is now shifting to the so-called support cells of the brain, glia. In neurodegenerative diseases and stroke, glia play roles in the pathogenesis of disease. Therefore, replacing them or enhancing their functions to ultimately save...
Microglia are tiny glial cells ("micro" means small). They act as the brain's own dedicated immune system. The brain needs its own immune system because the blood-brain barrier isolates the brain from the rest of your body.1 Microglia are alert to signs of injury and disease. When they ...
Glial cells make up theotherbrain cells. They are a diverse group of cells that are versatile in their range of functions. Glial cells were first discovered in 1838 by Robert Remak. He discovered Schwann cells (named after Theodor Schwann, who confirmed Remak’s discovery), which are a type...
Since glial cells play critical roles in brain development and function, we hypothesized that CPF neurotoxicity involves alteration of glial cell development. ... SJ Garcia,FJ Seidler,TA Slotkin - 《Environmental Toxicology & Pharmacology》 被引量: 317发表: 2005年 加载更多来源...
Instead, recent compelling studies indicate that glial cells play more active and essential roles in brain development and brain function than previously acknowledged (Allen & Barres, 2005; Doetsch, 2003, Haydon, 2001; Seifert, Schilling, & Steinhauser, 2006). There are three types of glial cells...
explanation of the function of glial cells, given that their functions include myelination of the CNS, contribution to the blood–brain barrier, removal, recycling and storage of transmitter substances, control of the concentration of potassium ions in the perineuronal milieu and storage of glycogen....
Roles of glial cells in the formation, function, and maintenance of the neuromuscular junction Like other vertebrate synapses, the neuromuscular junction (NMJ) has glial cells that are closely associated with the pre- and post-synaptic components. Th... S Koirala,LV Reddy,CP Ko - 《Journal of...
cells that are involved in adaptive immune reactions do enter the brain, and this can result in major CNS pathology. Multiple sclerosis is an important example. Furthermore, immune reactions, often attributable to the innate immune system, feature in many, if not all, neurodegenerative diseases. ...
摘要: Reactive gliosis is a hallmark of Alzheimer's disease. Glial connexin expression is affected in this pathology. Connexins, but also pannexins hemichannels, are activated in glia. Astroglial connexins may contribute to neuronal damages in neurodegenerative diseases.关键词:...