Furthermore, the functions of PP1/Glc7 and the two Glc7-containing complexes are conserved in mammals to regulate autophagy and telomere structure. Collectively, our results reveal a novel mechanism that regulate gene expression and chromatin structure in response to glucose availability....
The proposal of the GlcA(3S)-containing structure for the disulfated and the trisulfated units was based on the elution positions on HPLC, the reactivity to the HNK-1 antibody, and the resistance to periodate oxidation. However, there is an apparent discrepancy between our findings and the ...
1989). Using extracts from Myc-tagged Glc7p containing cells as a negative control for immunoprecipitation with anti-HA antibody, no H3 phosphatase activity was detected in the immunoprecipitants. Finally, gel analyses showed that the substrates were not degraded and Western blot confirmed that the...