此外,交叉引用具有疾病遗传关联的组织特异性eQTL可以帮助识别与疾病生物学最相关的组织。我们使用GTEx试点数据检查了多个组织之间的eQTL共享,并利用较大的组织范围发现了弱但具有组成型活性的eQTL ② 我们调查了九种组织中每种组织的22286个基因(至少10个样本中RPKM> 0.1)的eQTL共享模式,并对每对组织进行了基于模型的...
Genotype-Tissue Expression (GTEx) 2012 BRN Symposium February 23, 2012 NHGRI: Jeff Struewing, Simona Volpi and Cathy Ng NIMH: Susan Koester and Roger Little Genotype-Tissue Expression (GTEx) NIH Common Fund (commonfund.nih.gov/gtex) Co-chairs – Eric Green, NHGRI & Tom Insel, NIMH Lead ...
We present an analysis of RNA sequencing data from 1641 samples across 43 tissues from 175 individuals, generated as part of the pilot phase of the Genotype-Tissue Expression (GTEx) project. We describe the landscape of gene expression across tissues, catalog thousands of tissue...
The Genotype-Tissue Expression (GTEx) project:基因组织表达(gtex)项目基因,项目,The,GTEx,the,基因表达 文档格式: .pdf 文档大小: 961.78K 文档页数: 13页 顶/踩数: 0/0 收藏人数: 0 评论次数: 0 文档热度: 文档分类: 论文--毕业论文 文档标签: ...
The GTEx project of the NIH Common Fund aims to establish a resource database and associated tissue bank in which to study the relationship between genetic variation and gene expression and other molecular phenotypes in multiple reference tissues (Supplementary Fig. 1). The GTEx project began with...
内容提示: OPEN580 volume 45 | NumBeR 6 | JuNe 2013 | nature geneticscommentary(and eventually completely sequenced), with genotyping data linked to genome-wide gene expression patterns across a wide range of tis-sue types. Initially, this resource would enable the research community to perform a...
(GTEx) project: www.gtexportal.org: RNA-SeQCv1.1.8 gene rpkm Pilot V3 patch1.The data was used to analyze how tissue samples are related to each other in terms of gene expression data The data can be used to get insights in how gene expression levels behave in in the different human...
Farm animal Genotype-Tissue Expression (FarmGTEx) 项目致力于通过全球科学家的合作,为家养动物构建一个全面的分子表型QTL数据库,从而帮助我们更好地解析重要经济性状以及环境适应性的分子遗传机制,同时促进新的育种手段(比如基因编辑)和比较基因组学的发展。
The cattle Genotype-Tissue Expression atlas v1. Contribute to shuliliu/cattleGTEx development by creating an account on GitHub.
The Genotype-Tissue Expression (GTEx) project. Nat. Genet. 45, 580–585 (2013). Ardlie, K.G. et al. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 348, 648–660 (2015). Article Google Scholar Pakstis, A.J. et al. SNPs for a...