DISEASES OF GENETIC ORIGINDISEASES OF GENETIC ORIGIN.doi:10.1016/S0140-6736(61)92609-5NoneElsevierLancet
Genetic Origin of Disease Complex Diseases: Research and Applications DNA Deletion and Duplication and the Associated Genetic Disorders Gene Interaction and Disease Genomic Imprinting and Patterns of Disease Inheritance Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders mtDNA and ...
et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature 514, 92–97 (2014). Article CAS PubMed PubMed Central Google Scholar Morris, A.P. et al. Large-scale association analysis provides insights into the genetic architecture and ...
They call them genetic freaks. Men with muscles the size of my head, and heads the size of my torso (see Barry Bonds). Their arms are nearly 2 feet in circumference, and their body fat percentages are in the single digits. Surely a body structure like this must be genetic in origin…...
Rare diseases (RD) affect a small number of people compared to the general population and are mostly genetic in origin. The first clinical signs often appear at birth or in childhood, and patients endure high levels of pain and progressive loss of autono
(Bacanu et al., 2002), (Avramopoulos et al., 2005), (Hollingworth et al., 2007)), or parent of origin effects, e.g. (Bassett et al., 2002). Results by (Ashley-Koch et al., 2005) and (Hahs et al., 2006) on Amish families were not considered due to the inclusion of MCI ...
To better understand the issue, a team led by Dr. Shi-Qing Cai at the Chinese Academy of Sciences analyzed the genetic origin of variability in the rate of aging by using Caenorhabditis elegans (C. elegans) as an animal model. C. elegans is a tiny free-living nematode with a length of...
The perturbations necessary to drive cancer expose vulnerabilities that are not present in the normal cell-of-origin. For example, the MSI that often leads to cancer simultaneously makes the inhibition of Werner syndrome ATP-dependent helicase (WRN) lethal to the tumor cells62,63. As theKRASallel...
Parent-of-origin testing of prenatal copy number variations: a retrospective study of 167 family cases Yuefang Liu Yuan Peng Qiong Pan ResearchOpen Access18 Feb 2025Scientific Reports Volume: 15, P: 5979 Real-world data analysis for factors influencing the quality check status in FoundationOne CDx...
Diseases Muscle Disorders Genetic tests for cancer You have a strong family history of canceror are diagnosed with cancer Genetic tests for rare diseases You are a parent of a child with a genetic disorderor with symptoms of unknown origin ...