The genetic code is degenerate, that is, several codons are translated into the same amino acid. Synonymous codon changes that do not alter the protein sequence were considered as having no functional consequence and referred to as 'silent'. This viewpoint has changed drastically in the past ...
1. GENETIC CAUSE OF RARE DISEASE MAY BE INVOLVED IN MORE COMMON BIRTH DEFECTS [J] . Anonymous American journal of medical genetics, Part A . 2011,第8期 机译:罕见疾病的遗传原因可能与更常见的出生缺陷有关 2. Implementing comprehensive genetic carrier screening in China―Harnessing the power...
- 《Journal of Neuroscience》 被引量: 636发表: 2009年 Familial mental retardation syndrome ATR-16 due to an inherited cryptic subtelomeric translocation, t(3;16)(q29;p13.3). In the search for genetic causes of mental retardation, we have studied a five-generation family that includes 10 ...
Individuals with Down syndrome have an enhanced risk of developing early onset Alzheimer disease. Here, the authors describe the features of Alzheimer disease in Down syndrome and show how understanding the genetic and pathogenic mechanisms of this form
糖尿病的病因(Thecauseofdiabetes) I.geneticfactors Diabeteshasbeenrecognizedasageneticdisease,andgenetic studieshaveshownthattheincidenceofdiabetesis significantlydifferentfromthatofnonrelativesamong relativesofdescent,theformerbeing5timeshigherthanthe latter.Theimportanceofgeneticfactorswas50%inthe etiologyoftype1diab...
Huntington disease, rare hereditary neurological disease characterized by irregular and involuntary movements of the muscles and progressive loss of cognitive ability. The disease was first described by American physician George Huntington in 1872. Learn
In the developing countries, it says, most of the environmental problems arecausedby underdevelopment. 出自-2016年6月阅读原文 These catastrophic eventscausedmore than 1.5 trillion dollars in economic losses. 出自-2016年6月听力原文 a basis for explaining human genetic diversityan aid to understanding ...
Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families. Cell Rep. 2015;10:148–161. Article CAS Google Scholar Karaca E, Harel T, Pehlivan D, et al. Genes that affect brain structure and function identified...
The Black Death is widely believed to have been the result ofplague, caused by infection with thebacteriumYersinia pestis. Modern genetic analyses indicate that the strain ofY. pestisintroduced during the Black Death is ancestral to allextantcirculatingY. pestisstrains known to cause disease in huma...
Genetic Curse Plea Goes out to Help the Cause; A Fundraising Evening Is Planned to Help in the Battle against a Disease That Can Follow Families Down ... D Examiner 被引量: 0发表: 0年 Accidents of Influence: Writing as a Woman and a Jew in America On T. S. Eliot: Geniuses and Ant...