genetic disorderancient DNAhuman migrationdisease concepthistorical perspectivegenetic disorderancient DNAhuman migrationdisease concepthistorical perspectiveThe historical aspects of genetic disorders are deduced from analysis of modern cases. Direct studies of DNA from ancient human remains could become integrated...
Down syndrome, the most common genetic cause of intellectual disabilities, was first described in 1866, during an era of great change in our understanding of genetics and evolution. Because of its importance, the history of research on Down syndrome parallels the history of human genetics. In man...
15.Throughout history, diseases such as the black plague have killed millions of people.在历史上,像黑死病这样的疾病,造成了数以百万计的人死亡。 16.Genetic Disorders of Cholesterol Biosynthesis-Pathophysiological Studies of Smith-Lemli-Opitz Syndrome;遗传性胆固醇合成缺陷性疾病的病理生理研究—史—伦—奥...
Deciphering Developmental Disorders Study. Prevalence and architecture of de novo mutations in developmental disorders. Nature 542, 433–438 (2017). Article CAS Google Scholar Splinter, K. et al. Effect of genetic diagnosis on patients with previously undiagnosed disease. N. Engl. J. Med. 379,...
The history of genetics refers to the development and evolution of the study of heredity, from Gregor Mendel's experiments on peas to the discovery of DNA as the carrier of genetic information by scientists like Francis Crick and James Watson. ...
Consistent with prior research, early age of onset appears to define a familial and, by extension, genetic subtype of major depressive disorder. 展开 关键词: Family History Major depressive disorder DOI: 10.1016/j.jpsychires.2006.02.005 被引量: 123 ...
such as the ability to visualize human chromosomes, the development of methods to study biochemical variations in blood and urine, cell culture, somatic cell hybrid- ization, and molecular technology, all of which allowed for the diagnosis, treatment, and prevention of genetic disorders in children...
and communal resting or sleeping. While there had been early mentions of fruit fly aggression12,13,14, research on the topic has intensified relatively recently owing to their adoption for neurobiological and genetic analyses of aggression5,6,15. Similar to aggression, hints of fruit fly sociabilit...
Family history of psychiatric disorders as a risk factor for maternal postpartum depression: a systematic review protocol. Accessed July 19, 2022. https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=277998 40. Kjeldsen MZ, Bricca A, Liu X, Frokjaer VG, Madsen ...