Twitter Google Share on Facebook epistasis (redirected fromGenetic interactions) Thesaurus Medical Encyclopedia e·pis·ta·sis (ĭ-pĭs′tə-sĭs) n.pl.e·pis·ta·ses(-sēz′) 1.An interaction between nonallelic genes in which the genotype at one locus affects the expression of alleles...
We modeled the pathway network as Bayesian network and applied this model to infer pathways for the coherent subsets of the global genetic interaction profiles, and the available data set of endoplasmic reticulum genes. The protein interaction data were derived from the BioGRID database. Our method...
Target of AED: we assessed whether the gene is a known target of an anti-epileptic drug, as detailed in the drug–gene interaction database (www.DGidb.com; accessed on 26-11-2021) and a list of drug targets from a recent publication (Supplementary Data 10)88. Knockout mouse: we assess...
Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M: BioGRID: a general repository for interaction datasets. Nucleic Acids Res. 2006, D535-539. 10.1093/nar/gkj109. 34 Database Goldberg J, Huang HB, Kwon YG, Greengard P, Nairn AC, Kuriyan J: Three-dimensional struc...
et al. DGIdb 3.0: a redesign and expansion of the drug–gene interaction database. Nucleic Acids Res. 46, D1068–D1073 (2018). Article CAS PubMed Google Scholar Young, M. D., Wakefield, M. J., Smyth, G. K. & Oshlack, A. Gene ontology analysis for RNA-seq: accounting for ...
The BioGRID interaction database: integration of genetic, protein and chemical interactions and an improved network viewerRose OughtredBobbyJoe BreitkreutzLorrie BoucherChristie S. ChangJennifer M. RustAndrew ChatraryamontriNadine KolasLara O'Donnell...
Although this particular interaction needs to be reconfirmed, this study illustrates, in addition to replication, one of the other essential next steps after gene-finding: studying the interactions with other genes and with environmental factors. Interactions are assumed to play a fundamental role ...
A.A. Freitas, Understanding the crucial differences between classification and discovery of association rules—a... A.A. Freitas, Understanding the Crucial Role of Attribute Interaction in Data Mining, Artificial Intelligence Review,...View more references ...
Ecological validity of social interaction tests in rats and mice. Genes Brain Behav. 2019;18:e12525. Article PubMed Google Scholar Jensen P. Behavior genetics and the domestication of animals. Annu Rev Anim Biosci. 2014;2:85–104. Article PubMed Google Scholar Axelsson E, Ratnakumar A, ...
Functional studies that further explore the relationship between Collinsella, lipid metabolism, and inflammatory signals would help to elucidate how their interaction influences AD and other diseases. Three genera of the Firmicutes phylum—Eubacterium nodatum group, Eisenbergiella, and Eubacterium fissi...