The present invention discloses polypeptides and genes suitable as targets for the development of new therapies to treat conditions associated with mitochondrial dysfunction, ameliorate or prevent. The invention also relates to methods of treating the condition, ameliorating or preventing, and also relates...
To interrogate changes in DNA methylation, we employed enzymatic methyl sequencing (EM-seq) of selected genes involved in key aspects of exercise adaptation such as myogenesis, gene regulation, angiogenesis, and metabolism and/or shown to be differentially expressed between groups at baseline or in r...
The shoot SEGs were enriched in functions involving the plant-type cell wall organization, biogenesis and mitochondrial mRNA processing (supplementary fig. 10, Supplementary Material online).Fig. 5. Shoot SEGs and their evolutionary model. (A) SEGs of shoots in P. edulis. RO, root; LB, leaf;...
Scarpulla, R.C. Nuclear activators and coactivators in mammalian mitochondrial biogenesis.Biochim. Biophys. Acta1576, 1–14 (2002). ArticleCASGoogle Scholar Brown, G.C. Control of respiration and ATP synthesis in mammalian mitochondria and cells.Biochem. J.284, 1–13 (1992). ...
The genes involved in ribosome biogenesis and assembly process were only frequently observed among the genes with an up-regulated pattern of expression induced by Xoo and Mor (Fig. 2 and Fig. 5). And the signal transduction process was only observed among the genes down-regulated by Mor (Fig...
Using tetrapolarityS. commune MAT-Agenes as a reference with pfam domain to predict and identify conserved domains [70], we identifiedMAT-Agenes in the genome. The mitochondrial intermediate peptidase gene (mip) was identified in the same manner.MAT-Bgenes include pheromone and pheromone precursors...
These nuclear-encoded genes act to suppress male sterility associated with cytoplasmic male sterility (CMS), a phenomenon related to the expression of mitochondrially-encoded sterility-associated genes. Rf genes identified thus far in petunia, rice and radish belong to the P subfamily of PPR genes ...
Data on gene expression or protein activity of the mitochondrial isoforms of PEPCK and ME in response to energy or protein supply are scarce in lactating bovine mammary glands. Because intramammary BCAA catabolism increased with PT, we hypothesized that PCK2 and ME2 expression would increase to ...
In particular, we found that genes involved in the synaptic transmission, in the endoplasmic reticulum membrane, cell adhesion, protein complex biogenesis and, in particular, the ribonucleoprotein complex are represented in the intersection of 1498 genes, which fall into both of RGD QTL and QTL1/...
several lineages retain mitochondrial genome coding capacities typical for their clade. CII indicates retention of (some) complex II subunits; ccm indicates retention of subunits of the multicomponent bacteria-derived c-type cytochrome biogenesis system. Purple lineage: largest set of mitochondrial genes;...