In addition to rare primary mitochondrial disorders, these mitochondrial-related genes are often associated with many common diseases. For example, in neurodegenerative diseases such as Parkinson's, Alzheimer's, and Huntington disease, mitochondrial and energy metabolism abnormalities can greatly affect ...
Effects of mutations in mitochondrial dynamics-related genes on the mitochondrial response to ultraviolet C radiation in developing Caenorhabditis elegans. Bess AS,Leung MC,Ryde IT,et al. Worm . 2013Bess AS, Leung MCK, Ryde IT, Rooney JP, Hinton DE, Meyer JN. Effects of mutations in ...
Premature ovarian insufficiency (POI) is a reproductive disorder characterized by the cessation of ovarian function before the age of 40. Although mitochondrial dysfunction and immune disorders are believed to contribute to ovarian damage in POI, the int
The introns are distributed in eight of the 15 protein coding genes. These introns contain a total of 61,092 nt (∼45.3% of the whole mitochondrial genome) and include representatives of most of the group I introns so far found in mitochondrial genomes of Basidiomycota. The plasmid-like ...
Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes. Blood Press. 19, 196–205 (2010). Article CAS PubMed Google Scholar Kuno, A. et al. Resveratrol ameliorates mitophagy disturbance and ...
The most differentially expressed genes in men were those related to oxidative phosphorylation, while in women were those involved in cell proliferation via AKT signaling [86]. mTOR is another major regulator of myocyte homeostasis [13]. Hyperactivation of mTOR during aging has a negative impact on...
The complete mitochondrial genome of Praia tianmunica is 15,556 bp long. It contains 37 genes and a control region of 505 bp in length. Gene rearrangement is present in the mitogenome of P. tianmunica. The maximum-likelihood and Bayesian phylogenetic analyses showed that the genus Praia was ...
The mitogenome is a double-stranded circular molecule of 15,805 bp in length with 22 transfer RNA genes, 13 protein-coding genes (PCGs), 2 ribosomal RNA genes as in other insects. To estimate the taxonomic status of Prionoceridae, total of 9 species from 5 families of Cleroidea were ...
[2]. Finally, in addition to the 13 housekeeping genes also found in animals, plants contain numerous open reading flames (ORFs) with unknown functions as well as genes with known functions, such as ribosomal protein subunit-encoding genes, that are not observed in the animal genomes. Although...
van Rooij, E. et al. A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.Dev. Cell17, 662–673 (2009). ArticleCASGoogle Scholar Kusano, K.F. et al. Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic sig...