encoding genes are located in IBD susceptibility loci provide strong arguments for further exploration of the role of CLRs in IBD.METHODS: In this study, we selected four single nucleotide polymorphisms (SNPs) in different CLRs to determine whether there could be a role for these CLRs in IBD. ...
If resistance genes for both antibiotics and biocides/metals are physically located on the same plasmid, metal/biocide exposure can also promote horizontal gene transfer (HGT) of antibiotic resistance. Today, conjugative plasmids carrying ARGs have become a major health challenge in clinical settings [...
Many of these genes, namely, IFNGR2, FOSL2, STAT3, FCGR2A, IRF8 and ZFP36L2 (Supplementary Note) are located within known IBD-associated loci and have immune functions. cTWAS also identified new genes in the loci whose associations fall below the standard GWAS cutoff. Some of these genes...
The Fe (II)- and α-ketoglutarate-dependent AlkB family dioxygenases are implicated in nucleotide demethylation. AlkB homolog1 (ALKBH1) is shown to demethylate DNA adenine methylation (6mA) preferentially from single-stranded or unpaired DNA, while its demethylase activity and function in the chrom...
For resistance to rifampin, a nucleotide substitution in rpoB gene is responsible, impacting the inhibition of bacterial transcription by interacting with beta-subunit of bacterial DNA-dependent RNA polymerase [20]. The main purpose of this study was to conduct a literature review to extract genes ...
The phenotypic evaluation data showed a wide continuous distribution, with heritability values ranging from 0.58 to 0.84. Thirteen single nucleotide polymorphisms (SNPs) were identified, significantly associated with leaf scald resistance. Among these, eight were stable across multiple environments and ...
Single nucleotide polymorphism in mce operons We used a discovery platform consisting of four standard reference strains (H37Rv, H37Ra, LVS (Low Virulent Strain) and BCG) and 12 clinical isolates selected at random. Overlapping primers were designed to map eight genes each of mce1 and mce4 ...
Four genes located on a SSC2 meat quality QTL region are associated with different meat quality traits in Landrace x Chinese-European crossbred population... S. Čepica,C. Óvilo,M. Masopust,... - 《Animal Genetics》 被引量: 12发表: 2012年 Four genes located on a SSC2 meat quality...
In addition to the PON1 gene (PON1), related genes designated PON2 and PON3 have been identified in the human genome and are linked with PON1 on chromo- some 7q21-q22 (Primo-Parmo et al. 1996). Two single nucleotide polymorphisms (SNPs), 584A fi G (Gln192 Arg; GenBank accession ...
KIF14 is required during the cell cycle and reaches its peak in the G2/M phase [135]. It is located in the cytoplasm during interphase; during prophase and metaphase accumulates at the developing spindle poles and their associated microtubules [135] (Fig.1). During anaphase KIF14 localizes...