From a cDNA library, a nucleotide sequence of a novel gene, called rig, specifically expressed by streptozotocin- or alloxan-nicotinamide-induced rat insulinomas was determined and an amino acid sequence of a protein encoded by the gene was deduced. Further, novel genes with base sequences ...
Unique substitution of Asp57 with Ser in the A beta chain is considered to make the A beta gene the MHC-linked susceptibility gene. We therefore analysed the nucleotide sequences of the A beta second exon in ILI, CTS, and NON mice, which are nondiabetic inbred strains but are derived ...
What are single nucleotide polymorphisms (SNPs)? From SNPs to Genes: Disease Association at the Gene Level SNP Detection and Analysis Rapid SNP Detection and Genotyping of Bacterial Pathogens by Pyrosequencing Genetic diversity and signatures of sel...
European ancestry and polymorphisms in DNA repair genes modify the risk of melanoma: a case-control study in a high UV index region in Brazil. Melanoma, Case-control, DNA repair gene polymorphisms, XPC, Nucleotide excision repairUV radiation is the major environmental factor related to development...
3l). These findings indicate that MIF has a significant impact on correcting nucleotide misincorporation in vivo. MIF is recruited to the nucleus and locates at the DNA replication site in the S phase MIF primarily locates in the cytosol under physiological conditions. Next, we questioned when ...
et al. Chronic ethanol treatment alters purine nucleotide hydrolysis and nucleotidase gene expression pattern in zebrafish brain. Neurotoxicology 32, 871–878. https://doi.org/10.1016/j.neuro.2011.05.010 (2011). Article CAS PubMed Google Scholar Rico, E. P. et al. Adenosine deaminase activity...
CT60 single nucleotide polymorphisms of the cytotoxic T-lymphocyte-associated antigen-4 gene region is associated with Graves' disease in an Italian population 来自 国家科技图书文献中心 喜欢 0 阅读量: 44 作者: A Petrone,G Giorgi,A Galgani,I Alemanno,SM Corsello,A Signore,UD Mario,L Nisticò...
aThis gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia...
nucleotide and amino acid sequences of all immunologically relevant regions (FR1, CDR1, ..., CDR3, etc..) identified V, D, J, C genes comprehensive information on nucleotide and amino acid mutations positions of all immunologically relevant points in output sequences ...
B6 mice carrying a repaired (Edited)Gabra2allele (Edited/B6 mice) and crossed them with 129.Scn1a+/−mice to ascertain effects on Dravet phenotypes. We observed rescue of seizure, survival and neuronal phenotypes with this single nucleotide repair, validatingGabra2as an epilepsy modifier gene....