作为一本国际化的学术期刊,‘Genes & Diseases’不仅吸引了全球范围内的顶尖学者和研究团队投稿,还通过其开放的获取政策,为全球读者提供了便捷的获取途径,进一步推动了该领域知识的传播与交流。 影响因子的定义与重要性 影响因子(Impact Factor,简称IF)是评价学术期刊影响力的重...
In this work, to circumvent this issue and elucidate the impact of diseases on the transcriptome program at a large scale and in a principled way, we propose a reverse transcriptome-wide Mendelian randomization approach (revTWMR), which integrates summary-level data from GWAS andtrans-eQTLs studi...
Genes & Diseases About the journal About the Journal Genes & Diseasesis a journal for molecular and translational medicine. The journal primarily focuses on publishing investigations on the molecular bases and experimental therapeutics of human diseases. Publication formats include full length research ...
and research watch. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of human diseases. Emphasis will be placed on hypothesis-driven, mechanistic studies relevant to pathogenesis and/or experimental therapeutic...
publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of human diseases. Emphasis will be placed on hypothesis-driven, mechanistic studies relevant to pathogenesis and/or experimental therapeutics of human diseases. The journal has...
Genes, epigenetic regulation and environmental factors: Which is the most relevant in developing autoimmune diseases? Autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis and inflammatory bowel disease, have complex pathogenese... KH Costenbader,S Gay,ME Alarcó...
Introduction: The global impact of infectious diseases is tremendous. In 1996, the 17 million deaths from infectious diseases accounted for one third of all deaths worldwide, while the acute and chronic morbidity from infectious diseases adds an additional great burden on global health. Multiple fac...
For centuries, clinicians and scientists have sought to understand the etiology of disease. While some diseases can be traced back to a single factor, the etiology of complex diseases is more difficult to discern, in part due to the combinatorial nature of various contributing factors. One such ...
Illum LRH, Bak ST, Lund S, Nielsen AL (2018) DNA methylation in epigenetic inheritance of metabolic diseases through the male germ line. J Mol Endocrinol 60:R39–R56 Article PubMed Google Scholar Immler S, Pryke SR, Birkhead TR, Griffith SC (2010) Pronounced within-individual plasticity ...
and temporal lobes, has as yet to be elucidated13. The role of DNA-methylation is well established in the field of cancer14, where it showed promising clinical and preclinical results with the development of drugs targeting chromatin regulators15. For neurological diseases and dementia, the role ...