Significance of gene variants for the functional biogeography of the near-surface Atlantic Ocean microbiome Leon Dlugosch, Anja Poehlein, Bernd Wemheuer, Birgit Pfeiffer, Thomas H. Badewien, Rolf Daniel & Meinhard Simon Nature Communications volume 13, Article number: 456 (2022) Cite this...
The researchers used large-scale detection of DNA polymorphisms in about 26,000 people who reported having had same-sex partners and while they did discover a range of genetic variants linked to the trait, their effects were not enough to predict a person's sexual behaviour. "Overall, our res...
Over 4 million coding mutations have been identified across all human cancer disease types.COSMIC(Catalogue OfSomatic MutationsIn Cancer database) describes 10 million non-coding mutations, 1 million copy-number aberrations, 9 million gene-expression variants, and almost 8 million differentially methylate...
[C]基因the basic part of a living cell that contains characteristics of one's parents gene是什么意思 n.基因 gene变形 复数:genes gene英英释义 Noun 1. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA...
More dimensions of the 3D genome Advances aim to capture comprehensive, dynamic genome structures in living cells. Lei Tang Comments & Opinion06 Dec 2024Nature Methods Volume: 21, P: 2229 Context-specific regulatory variants in precision medicine and agriculture ...
Include insertions, deletions, translocations, duplications, and copy number variants. • Indels: Nucleotide sequences inserted or deleted, typically less than 100 nucleotides. • Gene conversion: Interchanging one sequence with a homologue, producing a hybrid gene. • Hybrid gene: Product of ...
We also investigated the differences between gene PAVs and other variants from their site frequency spectra (SFS). The SFS contains the presence frequency for the gene PAVs and SVs, as well as the derived allele frequency of fourfold SNPs. The derived allele and ancestral alleles are defined ...
Li B, Leal SM (2008) Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am J Hum Genet 83:311–321. https://doi.org/10.1016/j.ajhg.2008.06.024 Article CAS PubMed PubMed Central Google Scholar Liu TC, Stappenbeck TS (201...
Ultimately, genetic studies may lead to improved understanding of biological processes and offer potential for targeted interventions for prevention or treatment of cancer. However, cancer genes involve complex pathways with multiple potentially important allelic variants (Vogelstein and Kinzler, 2004). ...
community of cells formed a well-defined entity. Several progenote descendants were probably able to cross the Darwinian threshold, out of which three major variants evolved to form the now known domains of life: Bacteria, Archae and Eucarya. After this evolutionary time point inheritance was ...