Pasquesi set out to challenge this assumption, looking for gene variants formed by transposons that were actually important for human immune function. When she analyzed state-of-the-art genetic sequencing data fromhuman tissuesand cells, she found 125 instances across 99 genes. A break in the ant...
Comparative analysis of glideosome components.A. Table of presence/absence of genes encoding glideosome proteins, distributed into functional groups. Glideosome components have been described mainly inT. gondiiandP. falciparum. Protein sequences were searched for in the genomes of bothPorosporaand a...
7b, c). To test the functional relevance of this motif, we replaced the native porin genes with alleles encoding porin variants in which the aspartic acid residue (D71) in the center of the loop was replaced by serine (Supplementary Fig. 8a). When introduced into Por39, the substitution ...
Thus, none of the deletions removed the ribosome binding signals of the nearby downstream gene, and the unaltered genes should be expressed normally. Phage particles were produced by induction of prophages to lytic growth with mitomycin C or by infection for wild-type particles, and highly ...
This is particularly true for genes encoding components of the photosynthetic apparatus, such as phycobiliproteins and PSII polypeptides. Some strains grown under light–dark cycles are capable of incorporating specific metabolic tasks into the swing of the cycle, relegating, for example, protein ...
The hAT transposons have been co-opted several times as a source of the coding sequence for the emergence of new genes and functions44. Even though domesticated proteins have evolved from intact transposases, it seems that their enzymatic activity is rarely retained, contrary to their DNA-binding...
This study provides the most comprehensive research on Egyptian AMV populations, focusing on the CP gene. Comparison of CP genes and phylogenetic analysis of Egyptian AMV isolates formed a distinct group (GPI) that was closely related to Gomchi isolate from South Korea. The study assessed antioxida...
(E) Distribution of the longest upstream open reading frame (uORF) in genes that are expressed at the 18 h stage and that show high 5′ UTR coverage and translational delay, in comparison to genes that have low 5′ UTR coverage and no translational delay. The difference in distribution was...
Identifying genetic variants asso- ciated with neuroticism, but also with extraversion, has proven difficult. Suggestive linkage has been reported for several chromosomal regions with only few replications.21–27 Candi- date studies have reported associations with markers within several genes,28–32 ...
In all of the genetic markers here examined, no obvious abnormalities were observed, and it was considered that the genes for these markers were still retained in the chromosomes of these patients. 41. Evidence for Close Genetic Linkage between HLA and Congenital Adrenal Hyper- plasia Loci: ...