Cheminformgem -Difluoromethylation of α- and γ-ketoesters: preparation of gem -difluorinated α-hydroxyesters and γ-butyrolactones[J] . Manat Pohmakotr,Duanghathai Panichakul,Patoomratana Tuchinda,Vichai Reutrakul.Tetrahedron . 2007 (38)...
PhSCF2SiMe3 has been demonstrated as difluoromethyl carbanion synthon (-CF2H). It reacts chemoselectively with alpha-and gamma-ketoesters at the keto group in the presence of a catalytic amount of TBAF in THF to give the corresponding alpha-hydroxy ester adducts as well as gamma-gem-...
gem-Difluoromethylation of - and -Ketoesters: Preparation of gem-Difluorinated -Hydroxyesters and -Butyrolactones.hydroxycarboxylic acids (ether carboxylic acids) and esters (benzene compounds)furan derivativesC‐C bond formationChemInform is a weekly Abstracting Service, delivering concise information at...
DengJin-HongLinJianZhengJi-ChangXiaoChemical communications (Cambridge, England)Deng, X.-Y., Lin, J.-H., Zheng, J. & Xiao, J.-C. Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylation. Chem. Commun. 51, 8805-8808 (2015)....
Zhu, L.; Li, Y.; Zhao, Y.; Hu, J. Nucleophilic (phenylsulfonyl)- difluoromethylation of alkyl halides using PhSO2CF2SiMe3: preparation of gem-difluoroalkenes and trifluoromethyl compounds. Tetrahedron Lett. 2010, 51, 6150-6152.Zhu, L., Li, Y., Zhao, Y., Hu, J. (2010). ...
Jinbo HuWILEY‐VCH VerlagZhu, L.; Li, Y.; Zhao, Y.; Hu, J. Nucleophilic (phenylsulfonyl)- difluoromethylation of alkyl halides using PhSO2CF2SiMe3: preparation of gem-difluoroalkenes and trifluoromethyl compounds. Tetrahedron Lett. 2010, 51, 6150-6152....
Spiroisoxazoline via intramol cyclization/methylation 5,5-disub isoxazoline [nitrileoxide dipolar cycloadd gem-disub alkene]Hamme, A T
Dep. Chem.Vichai ReutrakulDep. Chem.Manat PohmakotrDep. Chem.ChemInformNucleophilic gem ‐Difluoro(phenylsulfanyl)methylation of Carbonyl Compounds with PhSCF2H in the Presence of a Phosphazene as a Base[J] . Teerachai Punirun,Darunee Soorukram,Chutima Kuhakarn,Vichai Reutrakul,Manat Pohmako...
The Fe(dbm) 3 catalyst promoted dimethylations of GEM-dichlorocyclopropanes in the presence of 4-methoxytoluene or P-xylene. In contrast, CoCl 2(dppe) conducted their hydrodechlorination.doi:10.1055/s-1998-1581Yoshinori NishiiKazunori Wakasugi...
Direct nucleophilic gem-difluoro(phenylsulfanyl)methylation of carbonyl compounds has been achieved by use of difluoro(phenylsulfanyl)methane (PhSCF2H) and the phosphazene base P4-tBu in THF. Non-enolizable aldehydes and ketones are suitable substrates to undergo nucleophilic gem-difluoro(phenyl...