binding site of G1. Finally, to tighten up the gelsolin–actin complex, Ca2+binds to the two type-1 sites shared between actin and gelsolin, which might explain the very high affinity of gelsolin to actin as recently demonstrated for plant villin, a gelsolin-like protein (Mierset al., ...
Distribution of a gelsolin-like 74,000 mol. wt protein in neural and endocrine tissues - Sakurai, Ohmi, et al. - 1990Sakurai T, Ohmi K, Kurokawa H, Nonomura Y. 1990. Distribution of a gelsolin-like 74,000 mol. wt. protein in neural and endocrine tissues. Neuroscience 38:743-756....
Taniuchi, K.; Furihata, M.; Naganuma, S.; Dabanaka, K.; Hanazaki, K.; Saibara, T. Podocalyxin-like protein, linked to poor prognosis of pancreatic cancers, promotes cell invasion by binding to gelsolin. Cancer Sci. 2016, 107, 1430-1442. [CrossRef] [PubMed]...
Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro. Oncogene. 2004;23(42):6997–7004. https://doi.org/10.1038/sj.onc.1207925. Alessi DR et al. Dec., Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 1996;15...
Gelsolin is a 80 kDa protein displaying six homologous, gelsolin-like, domains (named G1 to G6) existing as two alternative splicing variants: a 24-residue shorter intracellular form and a variant secreted in the bloodstream1,2. Both isoforms bind actin fibrils, severing the filaments and ...
Gelsolin is an actin-regulatory protein comprising six domains. It exists in two major forms: cytoplasmic and plasma gelsolin, and the latter contains an extra signal peptide (24 amino acids)1,2. The cytoplasmic form plays a critical role in remodelling the actin cytoskeleton during cell movement...
1987: Organization of stress fibers in cultured fibroblasts after extraction of actin with bovine brain gelsolin-like protein Experimental Cell Research 173(1): 244-255 Doi, Y.K.; Banba, M.; Vertut-Doï, A. 1991: Cysteine-374 of actin resides at the gelsolin contact site in the EGTA-...
Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin - Wang, Xie, et al. - 2003 () Citation Context ... tyrosine kinase, is another nonreceptor protein kinase closely related to FAK. It is found in high amounts in endothelial ...
A gelsolin-like protein from Papaver rhoeas pollen (PrABP80) stimulates calcium-regulated severing and depolymerization of actin filaments. Huang Shanjin,Blanchoin Laurent,Chaudhry Faisal,Franklin-Tong Vernonica E,Staiger Christopher J. Journal of Biological Chemistry . 2004...
Ying, "Overexpression of gelsolin-like actin-capping protein is associated with progres- sion of lung adenocarcinoma," Tohoku Journal of Experimental Medicine, vol. 225, no. 2, pp. 95-101, 2011.Shao, F.; Zhang, R.; Don, L.; Ying, K. Overexpression of gelsolin-like actin-capping ...