prostate cancerAIM: To investigate the role of gelsolin-like actin-capping protein (CapG) in prostate cancer (PCa). MATERIALS & METHODS: CapG expression and its correlation with clinicopathological characters and patient prognosis were analyzed in 76 cases of PCa by immunohistochemis...
(previously known as gCap39, Mbh1 or MCP), an actin-capping protein, andcofilin, an actin-severing protein, have been reported to translocate to the nucleus in a phosphorylation-dependent manner. CapG is a gelsolin-like capping protein, and several reports have shown that CapG is at least...
The actin capping activity of capping protein (CP) is indirectly regulated by competing with other factors for filament binding, or directly by factors that bind CP and sterically inhibit its interactions with filaments. Other proteins interact with CP t
Actin polymerization in cells occurs via filament elongation at the barbed end. Proteins that cap the barbed end terminate this elongation. Heterodimeric capping protein (CP) is an abundant and ubiquitous protein that caps the barbed end. We find that the mouse homolog of the adaptor protein CARMI...
Heterodimeric capping protein (CP/CapZ) is an essential factor for the assembly of branched actin networks, which push against cellular membranes to drive a large variety of cellular processes. Aside from terminating filament growth, CP potentiates the n
(1988) A 36 kDa monomeric protein and its complex with a 10 kDa protein both isolated from bovine aorta are calpactin-like proteins that differ in their Ca2+-dependent calmodulin-binding and actin-severing properties.Biochem. J. 251, 777–85. PubMed Google Scholar Maruta, H. &Isenberg, ...
In addition, CAPZB is known to increase actin filament depolymerization and capping, which promotes cell motility [10, 11], although functions other than cell motility have not been reported so far. According to the Human Protein Atlas (http://www.proteinatlas.org), CAPZB is also expressed in...
In addition, CAPZB is known to increase actin filament depolymerization and capping, which promotes cell motility [10, 11], although functions other than cell motility have not been reported so far. According to the Human Protein Atlas (http://www.proteinatlas.org), CAPZB is also expressed in...
Ying, "Overexpression of gelsolin-like actin-capping protein is associated with progres- sion of lung adenocarcinoma," Tohoku Journal of Experimental Medicine, vol. 225, no. 2, pp. 95-101, 2011.Shao, F.; Zhang, R.; Don, L.; Ying, K. Overexpression of gelsolin-like actin-capping ...
Clinical significance of gelsolin-like actin-capping protein expression in oral carcinogenesis: an immunohistochemical study of premalignant and malignant lesions of the oral cavity. BMC Cancer 2008;8:39. 锛Nomura H, Uzawa K, Ishigami T, Kouzu Y, Koike H, Ogawara K, et al. Clinical sig- nifi...