Most gastrointestinal stromal tumors (GIST) harbor mutations in either the KIT proto-oncogene (KIT[OMIM 164920]; 80%) or platelet-derived growth factor receptor a (PDGFRA[OMIM 173490];15%) receptor tyrosine kinases1,2,3. However, up to 10% of GIST are found to have non-mutatedKITandPDGFRA...
Gastrointestinal stromal tumors (GISTs) are a rare type of tumor that can develop liver metastasis (LIM), significantly impacting the patient's prognosis. This study aimed to predict LIM in GIST patients by constructing machine learning (ML) algorithms to assist clinicians in the decision-making pr...
The epithelial cells of the gastrointestinal (GI) tract communicate with each other and with cells of other organs via a complex network of highly regulated movement of ions and biomolecules. The molecules ensure regulated activity of cells, tissues, and
The GEPIA database evaluated the expression of specific markers linked to immune cell infiltration as well as the relationship between NOTCH3 expression and patient prognosis in a variety of tumour types. Other genes of interest were displayed on the y-axis, while NOTCH3 was utilized for the x...